- All Journals
- Al-Qadisiyah University
- Basrah University
- Kirkuk University
- Mosul University
- The Iraqi Borad for Medical Specialization
- University of Anbar
- University of Technology
- Al Mustafa University
- Al-Zahraa University for Women
- Alnoor University
- Kunooz University
- Misan University
- Ninevah University
- Tikrit University
- University of Al-Hamdaniya
- University of Kerbala
HISTOLOGICAL AND BIOCHEMICAL STUDY ON EFFECT OF THE ORAL CONTRACEPTIVE PILLS IN EXPERIMENTAL MALE MICE | ||
| AL-TAQANI | ||
| Article 1, Volume 26, Issue 3, 2013, Pages 0-0 | ||
| Author | ||
| Wafeeq Nasser Hassan Al Esmaial | ||
| Abstract | ||
| The aim of this study is to find the effect of oral contraceptive pills(OCPs) on some biochemical parameters of the blood serum and histopathological changes in the testis and liver of the male mice.Eighteen adult male mice were divided randomly into edual three groups ; group I OCPs- untreated as control ,group II OCPs-treated with 0.00258g/kg daily for 15 days for biochemical study and group III OCPs- treated with 0.00258g/kg daily for 30 days for biochemical &histological study. The results showed that the oral contaceptive pills had caused significant increase (P<0.05 ) in GOT ,ALP enzymes and total cholesterol and significant decrease (P<0.05 ) in GPT enzyme , whereas total protein was not significanly changed. Histopathological changes were observed on testis as damage and destruction of seminal epithelial layer and redction of spermatogenesis, histolysis of interstitial tissue and damage in Leydig cells. Other histopathological changes were noticed in the liver including damage, hypertrophy in some cells and hyperplasia in different positions of other cells compared to control. | ||
|
Statistics Article View: 64 PDF Download: 6 |
||