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Histopathological evaluation of skin wound in rabbits treated by systemic dexamethasone. | ||
| Journal of baghdad college of dentistry | ||
| Article 1, Volume 19, Issue 1, 2007, Pages 58-61 | ||
| Author | ||
| Muhannad A. Kashmoola | ||
| Abstract | ||
| ABSTRACTBackground: Healing of all damaged tissues including skin wounds has an identical pattern and depends on numerous intrinsic and extrinsic factors; one of these factors is cortisone hormone. The present study was designed to show the effect of dexamethasone on skin wound healing.Materials and methods: Twelve rabbits were used, experimental group (7 rabbits) were given 4 mg dexamethasone ten days prior to skin incision and control group (5 rabbits) had skin incision without medicament application. Biopsies were taken from two groups for histopathological evaluation.Results: There was a delay healing in the experimental group in comparison to control group.Conclusion: Prolonged use of dexamethasone or misuse of this drug impaired wound healing.Key words: Dexamethasone, skin wound. (J Bagh Coll Dentistry 2007; 19(1)58-61) | ||
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