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Evaluation of lipid-bound sialic acid tumor marker in sera of acute lymphocytic (ALL) patients | ||
| Journal of baghdad college of dentistry | ||
| Article 1, Volume 20, Issue 1, 2008, Pages 28-30 | ||
| Authors | ||
| Fawaz Al-Swad; Nazar G.A. Talabani; Abdul Wahab R. Hamad | ||
| Abstract | ||
| ABSTRACTBackground: Lipid-bound sialic acid (LSA) concentration was determined in the sera of 90 patients with acute lymphocytic leukemia (ALL) and 50 controls (30 normal subjects and 20 chronic non-malignant diseases). The aim of this work is to determine the reference values for serum sialic acid in healthy subjects and in patients with acute lymphocytic leukemia.Materials and Method: All of serum sample were collected by venepuncture and kept frozen (-20 C°) until analyzed, then a spectrophotometric technique is used for the estimation of the concentration of sialic acid marker in sera.Results: The mean sialic concentration in healthy individuals was 132 mg/ml and that in chronic non-malignant disease was 171.1 mg/ml, where as, the concentration of (LSA) in 90 cancer patients with (ALL) was 270.3 mg/ml.Conclusion: Both cancer patients with (ALL) and patients with chronic non-tumor disease can cause an elevation in the concentration of sialic acid values in serum as compared to healthy individuals.Keywords: Sialic acid, tumor marker, acute lymphocytic leukemia. (J Bagh Coll Dentistry 2008; 20(1)28-30) | ||
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