Significance of C-reactive protein in Neonatal Sepsis in Diyala Province, Iraq, Hospital Based Study

Assi Obaid, Kareem; Mukhaiber Mustafa, Falah; Mohsin Ali, Sabah

	Significance of C-reactive protein in Neonatal Sepsis in Diyala Province, Iraq, Hospital Based Study
Diyala Journal of Medicine
Article 1, Volume 9, Issue 1, 2015, Pages 53-61
Authors
Kareem Assi Obaid; Falah Mukhaiber Mustafa; Sabah Mohsin Ali
Abstract
Background: C-reactive protein is a well-recognized acute phase reactant that is greatly involved to support the diagnosis of neonatal septicemia. Objectives: To high light the correlation between C- reactive protein and neonatal septicemia. Patients and Method: A cross sectional study on hundred neonates infant demonstrated to have sepsis were studied during the period from 1st October 2014 to 28th February 2015. One group study was evaluated; age ranged from 29 week gestational age to 29 days post-natal. The data of patients in the group study collected from Al- Batool Teaching Hospital for Maternity and Children - neonatal intensive care unit. Result: There were 100 patients included in this study; that 61 patients (61%) were pre term (29 to 36 weeks gestational age), 39 patients (39%) were full term 37 weeks’ gestational weeks - 29 days post-natal). Males were 56 (56%), and females were 44 (44%). Fifty-seven (57%) were delivered by vaginal delivery; were as 43 (43%) delivered by caesarian section. The C- reactive protein level correlate well with the diagnosis of the neonatal sepsis as 86 (86%) patients had a positive result versus 14 (14%) who had negative results. Conclusions: C-reactive protein is very useful, cheep, and available test to confirm the diagnosis of neonatal sepsis and to follow the response of the patients to the antibiotic treatment.
Keywords
reactive protein; neonate; sepsis; Preterm

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