The Use of Diane – 35 in The Treatment of Infertility

Yousif, Abdaladeem; Mohsen Mohammed, Shaimaa

	The Use of Diane – 35 in The Treatment of Infertility
AL-yarmouk Journall
Article 1, Volume 9, Issue 9, 2017, Pages 158-164
Authors
Abdaladeem Yousif; Shaimaa mohsen mohammed
Abstract
Diane-35 is a hormonal compound of progesterone & oestrogen ( with anti-androgen effect ) used for the treatment of androgenic symptoms in females like severe cases of seborrhea & hirsuitism , it can also be used for cases of infertility . A case control study was performed about the use of diane-35 in the treatment of infertility in women with polycystic ovarian syndrome , the study included 589 infertile ladies with polycystic ovary , they were chosen among 3091 infertile ladies for other different causes attending Al-Diwaniyah maternity hospital & a private clinic in Samawa city from June 2009 until June 2011 .. 372 women were treated with diane-35plus induction of ovulation (inductionwithclomiphene + Gonal F) while 217 women were treated with induction alone , duration of treatment was 3-6 months according to patient response, the results showed that 220 out of 589 became pregnant while 369 did not , among those 220 pregnant ladies 186 were those treated with diane-35 plus ovulation induction while 34 were those treated with ovulation induction alone , this means that about 50% of ladies treated with diane-35 plus induction became pregnant while only 14% of ladies treated with only ovulation induction became pregnant .. We recommend that treatment modalities should be discussed with the patients including the success rates , cost , side effects , also cases of infertile polycystic ovaries that don"t respond to ovulation induction alone are better treated with diane-35 plus ovulation induction..

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