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Effect Aqueous Extract of Fenugreek Seeds on Some Biochemical Variables in Male Albino Mice with Induced Hyperproteinemia | ||
| Journal of Tikrit University For Agriculture Sciences | ||
| Article 1, Volume 18, Issue 1, 2018, Pages 166-171 | ||
| Authors | ||
| Mohammed Hameed Mahal; Othman Rashid AL Samarrai; Huda Abid Thamer | ||
| Abstract | ||
| This study was designed to determine the activity of aqueous extract of fenugreek seeds toward some of biochemical variables in mice with induced hyperproteinemia. The mice were distributed into three groups (10 mice per group), the first group was a control group, second group was treated with hyperproteinemia without treatment for two weeks, and third group was treated with hyperproteinemia and aqueous extract of fenugreek seeds at concentration 100 mg/kg of body weight for a period of two weeks. The results indicated that the hyperproteinemia induction in mice led to a significant increase in the levels of the total protein, urea, uric acid, triglycerides, and a significant decrease in levels of albumin, cholesterol and LDL-C, while the levels of glucose and HDL-C did not change compared with the first group (Control group). The results showed that oral administration with aqueous extract of fenugreek seeds at concentration 100 mg/kg body weight for two weeks led to a significant decrease in the levels of total protein, uric acid, triglycerides and LDL-C, while there was no significant difference in the levels of albumin, urea, glucose, cholesterol compared with the second group (Infected). | ||
| Keywords | ||
| fenugreek; Male Albino Mice; Hyperproteinemia; Cholesterol | ||
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