H. Abid, O., G. Mahdy, O. (2018). Formation of 1,5-Disubstituted 2-hydroxypyrroles via Reaction of 2-(Triphenylphosphoranylidene) succinic Anhydride with Schiff's Bases. , 11(2), 34-40. doi: 10.37652/juaps.2017.141587
Obaid H. Abid; Omar G. Mahdy. "Formation of 1,5-Disubstituted 2-hydroxypyrroles via Reaction of 2-(Triphenylphosphoranylidene) succinic Anhydride with Schiff's Bases". , 11, 2, 2018, 34-40. doi: 10.37652/juaps.2017.141587
H. Abid, O., G. Mahdy, O. (2018). 'Formation of 1,5-Disubstituted 2-hydroxypyrroles via Reaction of 2-(Triphenylphosphoranylidene) succinic Anhydride with Schiff's Bases', , 11(2), pp. 34-40. doi: 10.37652/juaps.2017.141587
H. Abid, O., G. Mahdy, O. Formation of 1,5-Disubstituted 2-hydroxypyrroles via Reaction of 2-(Triphenylphosphoranylidene) succinic Anhydride with Schiff's Bases. , 2018; 11(2): 34-40. doi: 10.37652/juaps.2017.141587

Formation of 1,5-Disubstituted 2-hydroxypyrroles via Reaction of 2-(Triphenylphosphoranylidene) succinic Anhydride with Schiff's Bases

Journal of University of Anbar for Pure Science
Article 9, Volume 11, Issue 2, 2017, Pages 34-40    PDF (1.11 M)
Document Type: Research Paper
DOI: 10.37652/juaps.2017.141587
Authors
Obaid H. Abid1; Omar G. Mahdy2
1University of Falluja
2University of Anbar College of Education for Pure Science
Abstract
Schiff's Bases were synthesized from the reaction of furfuraldehyde and substituted benzaldehyde with 4-aminoantipyrine and 2,4-dinitrophenylhydrazine and reacted with 2-(triphenylphosphoranylidene) succinic anhydride in an anhydrous 1,4- dioxane at reflux conditions. The resulting products were found to be 1,5-disubstituted 2-hydroxypyrroles. The structures of the products were confirmed by their melting points, FT-IR, 1HNMR spectra and C.H.N. elemental analyses.
Keywords
Schiff; Disubstituted; hydroxypyrroles
References
  1. Peter Vollhardt and Neil Schore, Organic Chemistry, 6th. Ed., W.H.Freeman And Company, New York, pp. 797- 800, (2011).
  2. William H. Brown, Brent L. Iverson, Eric V. Anslyn, Christopher S. Foote, Organic Chemistry, 7 Ed, WADSWORTH CENGAGE Learning, (2014).
  3. John Mcmurry, Organic Chemistry,  9 Ed, CENGAGE Learning,(2016).
  4. T.W. Graham Solomons, Craig B. Fryhle, Scott A. Snyder, Organic Chemistry, 11th Ed, John Wiley & Sons, Inc., Hoboken, New Jersey, (2014).
  5. Paula Yurkanis Bruice, Organic Chemistry, 7th. Ed , PEARSON ,811 ,(2014).
  6. L . G . W A D E , J R ., Organic Chemistry, 9th. Ed , PEARSON, pp. 732-733, (2013).
  7. J.A. Joule & K Mills, Heterocyclic Chemistry, 5th Ed., John Wiley & Sons, Ltd., puplication, Chap. 15-16,(2010).
  8. Theophil Eicher and Siegfried Hauptmann,The Chemistry of Heterocycles,2nd. Ed, WILEY-VCH GmbH & Co. KGaA , pp. 86-98,(2003).
  9. D. Curran, J. Grimshaw and S.D.Perera, Chem. Soc. Rev. Vol. 20, pp. 391, (1991).

10. Varun Bhard waj, Divya Gumber, Vikrant Abbot, Saurabh Dhiman and Poonam Sharma, Pyrrole: a resourceful small molecule in key medicinal hetero -aromatics, Royal Society of chemistry, RSC Adv.,5,15233 (2015).

11. T. Caryn, D. Matthew, Pyrrole Disorder for therapists, IJNPT, The neuropsychotherapist, issue 3, (2013).

12. M. T. Sarg, M. M. Koraa, A. H. Bayoumi, S. M. Abd El Gilil, Synthesis of Pyrroles and Condensed Pyrroles as Anti-Inflammatory Agents with Multiple Activities and Their Molecular Docking Study, Open Journal of Medicinal Chemistry, Vol. 5, pp. 49-96,(2015).

13. Anna Maria Almerico, Marco Tutone, and Antonino Lauria, A QSAR study investigating the potential anti-HIV-1 effect of some Acyclovir and Ganciclovir analogs, Issue in Honor of Prof Nicolò Vivona ARKIVOC, pp.85-94, (2009).

14. R. R. Gupta, M. Kumar, V. Gupta, Heterocyclic Chemistry, Vol.2, Springer- Verlag Berlin Heidelbery Gmbh, pp. 33-81, (1998).

15. Alan R.Katritzky,FRS, Heterocyclic Chemistry,Vol.5, Elsevier, pp82-90, (2012).

16. Richter, Indole and Pyrrole Synthesis, ''CliffsNotes'',group meeting (2004).

17. Dharmesh r. Dhameliya and mukesh c. Patel, synthesis, characterization and biological activity of novel pyrrole compounds, rasayan j.chem. Vol. 4, no. 3, pp. 580-584, (2011).

18. Umesh K. singh, surendra N. Pandeya, Sandeep K. Sethia, M. Pandey, A. Singh, Anuj Gary & Pawan Kumar,  ''Synthesis and Biological Evaluation of some sulfonamide Schiff's Bases'', IJPSDR, Vol.2, ISSne 3, pp 216- 218, (2010).

19. L.D.S.Yadav, Organic Spectroscopy, Springer Science,Business Media Dordrech, Springer-Science.Business Media, B.V. (2005).

20. Donald L. Pavia, Gary M. Lampman, George S.& James R. Vyryan, Introduction to spectroscopy, 4th Ed., Brooks cole cengage Learning, pp 16-104, (2009).

21. Robert M. Silverstein, Francis X. Webster, David J. Kiemle, spectrometric Identification of Organic compounds, 7th Ed, John- Wiley & Sons, INC., pp. 72-126, (2005).

Statistics
Article View: 530
PDF Download: 339


Journal Management System. Powered by iJournalPro.com