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Molecular characterization of β-Thalassemia patients in Wasit province | ||
| Journal Of Wassit For Science & Medicine | ||
| Article 1, Volume 9, Issue 2, 2016, Pages 70-77 | ||
| Abstract | ||
| Abstract Background: Hemoglobin-associated disorder is a different group of recessive genetic diseases. Which consist of the structural hemoglobin variants and the thalassemia.Aim of the study: to characterize the spectrum of beta globin gene mutations in patients with beta- thalassemia who are registered in thalassemia centers, Wasit, Iraq using PCR - based DNA diagnostic techniques. Patients and methods: The genomic DNA was extracted from 106 Iraqi patients with β-thalassemia major and intermedia from unrelated families and (50) healthy numbers as control were collected from Al-Kut Hospital, in Wasit province, to detect mutation using PCR - based DNA diagnostic techniques. . | ||
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