HISTOLOGICAL CHANGES IN SOME FEMALE RATS ORGANS INFECTED WITH TOXOPLASMA GONDII PARASITE ISOLATED FROM EMBRYO OF ABORTED SHEEP

H. Al-Delami, Liqaa; Hatim. Al-Sabawi, Buthaina; M.Basheer, Firas; I. Al-Sadi, Hafidh

	HISTOLOGICAL CHANGES IN SOME FEMALE RATS ORGANS INFECTED WITH TOXOPLASMA GONDII PARASITE ISOLATED FROM EMBRYO OF ABORTED SHEEP
Tikrit Journal of Pure Science
Article 1, Volume 23, Issue 1, 2018, Pages 13-18
Authors
Liqaa H. Al-Delami; Buthaina Hatim. Al-Sabawi; Firas M.Basheer; Hafidh I. Al-Sadi
Abstract
The current study included the identification of lesions and the histological changes caused by Toxoplasma gondii, which was isolated from embryos of aborted ewes. 15 female albino rats (3 months old) was injected intraperitonia with suspension containing 100 tissue cysts. After four months of injection, the histological section showed a chronic infection characterized by autolysis in all sections, where the liver sections showed expansion of the central hepatic veins, congestion in sinusoidal with irregularity in hepatic cords, and the presence of the parasites in the liver cells and Kupffer. The brain tissue showed vacuoles in the neurons with an increase in the number of Purkenji cells. Kidney sections were characterized by degenerative and necrotic changes in the endothelial cells of the proximal and distal convoluted tubules with Sloughing of necrotic and degenerated cells of the tubes, which accumulated inside the lumen. The parasites appeared in the endothelial cells of the glomerular tufts. Ovary and the uterus showed increased vascular wall thickness, furthermore, the spleen showed autolytic changes, pigment deposition with the presence of parasites within the cells.
Keywords
Toxoplasma gondii; Histopathological changes; sheep

Statistics Article View: 83 PDF Download: 41