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Efficacy of low level diode laser in skin wound healing (experimental study) | ||
| Journal of baghdad college of dentistry | ||
| Article 1, Volume 21, Issue 4, 2009, Pages 70-74 | ||
| Authors | ||
| AyadM. Ismael; Hussain A. Jawad; Ammar S. Al-Alawe | ||
| Abstract | ||
| ABSTRACTBackground: Wound healing is a complicated, interactive, integrative process involving cellular and chemotacticactivity, the release of chemical mediators and associated vascular response which includes number of phases:inflammatory phase, proliferative phase and remodeling phase. Low level laser therapy can be more effective in thethree overlapping phases of wound healing. Biostimulation appears to have an effect on the cellular level, byincreasing cellular function and stimulating various cells. The aim of present study was to evaluate histologically theefficacy of low level diode laser on skin wound healing in animal model (histological study).Material and methods: The experimental study was performed on seven healthy local bred rabbits. Four incisionswere done in each side at dorsal surface of each rabbit. The wounds at the right side were irradiated by low leveldiode laser while the wounds at left side were left without irradiation as a control group. Animals were divided intotwo groups according to laser parameters: 1- Group A includes three rabbits and the wounds were irradiated by1.25W/cm2 power density, 20 sec. exposure time. 2-Group B includes four rabbits and the wounds were irradiated by1W/cm2 power density, 50 sec. exposure time. Histological specimens were taken at 2nd, 3rd, 5th and 7th day formicroscopical examination concerning inflammatory cells infiltration and epithelial cell layer thickness.Results: Results show obvious reduction in inflammatory cell infiltration and more epithelization in laser treatedwounds compared with control wounds. Statistical analysis showed a significant difference between two groups.Conclusion: Low level diode laser (790-805nm) has beneficial effects in enhancement of soft tissue wound healingprocess histologically.Key words: Low level laser therapy, Diode laser, Wound healing, Biostimulation. (J Bagh Coll Dentistry 2009; 21(4): 70-74). | ||
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