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Evaluation of vitamin-D3 Concentration in Patients with Thalassemia in Baghdad City | ||
| Diyala Journal of Medicine | ||
| Article 1, Volume 14, Issue 1, 2018, Pages 10-19 | ||
| Authors | ||
| Ali Abdul Hussian Mahdi; Amal Azeez Kareem; Yousor Majid Jameel | ||
| Abstract | ||
| Background:Thalassemia is inherited blood disorders characterized by abnormal hemoglobin production. Objective:To evaluate decreasing in vitamin-D3 concentration in patients with thalassemia among healthy men in Baghdad city. Patients and Methods: In this study containing 99 thalassemia patients from Baghdad city (68 female and 31 male patients) and (31 healthy males and 10 healthy women) as a control group collected from Al-Kadhymia hospital. Their age ranged (15-40) years old which are compatible to age of study group. Serum samples taken from the patients to determined vitamin-D concentration by using Enzyme Linked Immuno Sorbent Assay (ELISA) technique, during the period 1st April 2016 to 28th January 2017. Results:The study revealed highly significant (P<0.01) low of vitamin-D3 concentration in patients with thalassemia (89.9% decrease vit-D3 compared with 10.1% control group vit-D3 concentration). Conclusion:The decreasing in vitamin-D3 concentration associated with thalassemia patients was due to less exposure to sun light that affected the vitamin metabolism in their bodies. | ||
| Keywords | ||
| Thalassemia; vitamin; concentration; ELISA | ||
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