- All Journals
- Al-Qadisiyah University
- Basrah University
- Kirkuk University
- Mosul University
- The Iraqi Borad for Medical Specialization
- University of Anbar
- University of Technology
- Al Mustafa University
- Al-Zahraa University for Women
- Alnoor University
- Kunooz University
- Misan University
- Ninevah University
- Tikrit University
- University of Al-Hamdaniya
- University of Kerbala
Effect Of renal diseases on some biochemical criteria in AL. Ramadi city | ||
| Journal of University of Anbar for Pure Science | ||
| Article 9, Volume 11, Issue 3, 2017, Pages 36-42 PDF (523.21 K) | ||
| Document Type: Research Paper | ||
| DOI: 10.37652/juaps.2017.145234 | ||
| Authors | ||
| Saeed Zidan Khalf1; Ezeddin Atea Albayyar2 | ||
| 1college education university of Al-anbar | ||
| 2College of Science, University of Anbar | ||
| Abstract | ||
| The present study has been done in Al-Ramadi Teaching Hospital in Al-Anbar governorate from 1/4/2016 to 1/10/2016.The study included 135 blood samples patients suffering from chronic renal diseases severe renal inflammation and renal gravel of as follows : (40) samples of blood for patients with chronic renal failure (15) samples for severe renal inflammation , (40) samples for renal gravel and in addition to the control group (40samples). The statistical results of this study has shown that there is moral rise (P<0.05) in the activity average of some enzymes ( AST, ALT , ALP ) in patients of chronic renal failure , severe renal inflammation and renal gravel as compared with the control group . The results also shown that there is moral rise (P<0.05)in the activity of enzyme GGT in patients of chronic renal failure only. On the contrary , the results in patients of severe renal inflammation and renal gravel are morally low ( P<0.05) as compared with the control group . The study also shown that there is a moral rise ( P<0.05) in the concentration of the total protein and globulin in patients of different kidney diseases as compared with the control group. The study showed a moral reduction (P<0.05) in the concentration of the albumin in patients with chronic renal failure and severe renal inflammation as compared with the control group . As for the results of the tests of total bilirubin there is a moral rise ( P<0.05)in patients with different renal diseases as compared with the control group. The study concluded that there is disorder in some of the hepatic function and the enzymic system in patients with different renal diseases in most of the studied biochemical aspects. | ||
| References | ||
|
[1] الجنابی, غصون غانم کعیم, (2005), تأثیر مرض ما قبل الشنج (PRE-ECLAMPSIA) فی النساء الحوامل على وظائف الکبد وأنزیمات القلب, رسالة ماجستیر, کلیة التربیة, جامعة کربلاء. [2] الدجیلی, علی عبد الزهرة مهدی.(2011): دراسة بعض التغیرات الفسلجیة والکیموحیویة المرافقة لمرضى الفشل الکلوی المزمن تحت الدیلزة الدمویة فی محافظة النجف الأشرف, رسالة ماجستیر, کلیة العلوم, جامعة الکوفة, قسم علوم الحیاة. [3] شاکر, أسیل کامل, (2008), بعض جوانب التغیرات الفسلجیة للمرضى المصابین بالفشل الکلوی, رسالة ماجستیر, کلیة الطب, جامعة بابل. [4] فلفل, عادل عبادی, (2010), بعض المؤشرات الجرثومیة والمناعیة لدى مرضى الفشل الکلوی المُزمن. رسالة ماجستیر ، کلیة العلوم ، جامعة بابل ، بابل – العراق. [5]المشهدانی, أحمد جاسم محمد(2014), وظائف الغدة الدرقیة وبروتین C التفاعلی لدى مرضى العجز الکلوی المزمن المستمرین على الدیلزة الدمویة ومرضى الزرع الکلوی, رسالة ماجستیر, کلیة التربیة للعلوم الصرفة, علوم الحیاة, جامعة دیالى. [6]Afshar , R .; Sanavi, S. ; Izadi - Khah, A.(2007). Assessment of Nutritional Status in Patients Undergoing Maintenance Hemodialysis A Single-Center Study From Iran". Saudi.J.kidney. Dis.Transplant .,18: 397-404.
[7]Al-Shammaa, N. M. J. ; Al- Wihaly, B. H . and Abass, E. A.A.( 2011).Effect Of Some Enzymes Activity In Liver Diseases From Patients Of Salmonella Paratyphi A With Iraqi Woman .Ibn Al- Haitham J. For Pure and Appl. Sci.,24:1-9.
[8]Boendermaker, A.E.; Boumans,, D.; van Zanten2, R.A.A.; Idzerda3, H.; vande Hout4, H.and Veneman Th.F.(2013). Elevated liver enzymes and renal ailure, with a surprising outcome. Two similar cases. Neth j crit care – volume 7 – no1.
[9]Boon AC, Bulmer AC, Coombes JS, Fassett RG. Circulating bilirubin and defense against kidney disease and cardiovascular mortality(2014). Mechanisms contributing to protection in clinical investigations. Am J Physiol Renal Physiol.;307:F123–136.
[10]Checherita, I. A. ; Turcu, F. ; Dragomirescu, R. F. and Ciocalteu, A. (2010). Chronic Complications in Hemodialysis : Correlations with Primary Renal Disease . Romanian Journal of Morphology Embryology, 51(1) : 21–26.
[11]David, L. N. and Michael, M.C. (2000). "Lehninger Principles Of Biochemistry" . 3 rd Ed , Worth Publisher., P623 – 655.
[12]Dhakad, R.K. ; Alam, S.I. ; Dixit , A. and Singh, L. (2005). "Purification and Characterization Of Thermo-Labile Alkaline Phosphatase From An Antarctic Pyschrotolerant Bacillus Sp P9". Enzyme and Microbial Technology., 36:855 – 61.
[13]Davidison S.,(1999):Principle and practice of medicine .7th ed.,Edwards C.R.W. ;Bouchier I.A.D. and Haslette C.,eds.,Churchill livingstone,p.112.
[14]Daze, D.C.( 2007). "The Role Of Existind and Novel Cardiac Biomarkers For Cardioprotection", Curr. Opin. Investi. Drugs. , 8: 711-717.
[15]Gendler , S .. Kaplan A. Clin Chem The C.V. Mosby Co.St Louis and Toronto. Princeton (1984) .Uric acid., 1268-1273 ; 425.
[16]Gong, N. ; Chen, C. ; Xie, L . ; Chen, H. ; Lin, X. and Zhang, R.(2005)."Characterization Of A Thermostable Alkaline Phosphatase From ANovel Species Thermus Yunnanensis Sp. Nov. and Investigation Of ItsCobalt Activation At High Temperature" Biochim Biophys Acta.,1750:103 – 11.
[17]Gornal,A.C.;Bardawill ,C.J.;and Dovid,M.M.(1949).J.Bio.Chem.p:177-179.
[18]Huang, X.-J. ; Choi, Y,-K. ; Im, H.-S. ; Yarimaga, O. ; Yoon, E. and Kim, H.-S.(2006). Aspartate Aminotransferase (Ast/Got) and Alanine Aminotransferase (Alt/Gpt) Detection Techniques. Sensors ., 6:756-782.
[19]Hruska, K.A. and Teitebaum, S.L.(1995). "Mechanism of Disease; Renal Osteodystrophy". Nut. Engl. J. Med ., 333: 166 -74.
[20]Jimmy, E. O.; Usoh2, F. ; Ekpo, A. J. and Umoh, I.( 2013). Serum Liver Enzymes As Markers In Assessing Physiologic Tolerance Of Amalar,Cotecxin, Chloroquine and Fansidar. European Journal Of Biology andMedical Science Research.,1: 24-30.
[21]Kaplan, L.A. ; Amadeo, J. P. and Steven, C. K. (2003). "Methods In Clinical Chemistry".4th Ed. Mosby – U.S.A., P113.
[22]Kind, P .R .N. and King, E.J. (1954). Estimation Of Platisma Phosphates By Determination Of Hydroixed Phenol With Amin. Antipyrine .Clin Path., 7:322-326.
[23]Lesafer¸ G.; Desmet¸ R.; and Lameire¸ N. (2000). Intradialytic removal of protein –bound uremic toxins: Role of solute characteristics and of dialyser membrane. Nephrol. Dial. Transplant .15: 50-70 .
[24]Liberato I, Lopes E, Cavalcante M, Pinto T, Moura I, and Júnior L (2012). Liver enzymes in patients with chronic kidney disease undergoing peritoneal dialysis and hemodialysis. Clinics (Sao Paulo). 67(2): 131–134.
[25]Porth C.M. (2007). Essentials of Pathology 2nd ed ,Lippincott Williams & Wilkins,Philadelphia;p:559-574.
[26]Ray, L.; Nanda, S. K.; Chatterjee, A.; Sarangi, R. and Ganguly S. (2015) A comparative study of serum aminotransferases in chronic kidney disease with and without end-stage renal disease: Need for new reference ranges. Int J Appl Basic Med Res; 5(1): 31–35.
[27]Reitman, S. and Frankal, S. . (1957) . A Colorimetric Method for the Determination of Serum Glutamic Oxalaloacetic and Glutamic Pyruvic Transaminases . Am J clin Patho , 28 : 56-59.
[28]Ross¸ D. L. (1995). Protein in chronic renal failure. J. Chem 15 13-15.
[29]Ryu S, Chang Y, Kim D, Kim Y, Suh B . (2007) γ-Glutamyltransferase as a Predictor of Chronic Kidney Disease in Nonhypertensive and Nondiabetic Korean Men. clinchem.
[30]Simon, H . (2003). Hepatitis , ADAM . Inc .,P1-3.
[31]Stephan P ., Gerda H.,Christoph G., Jasmin R., Mariella M., Maria K.,Nicole C., Clemens T., Christia M., and Alexander R.(2011). Relevance of gamma glutamytransferase – amarker for apoptotic balance – in predictingtumor stage and prognosis in cervical cancer. Gynecologiconocology. 122؛ P. 590-594.
[32]Yang, R. Z. ; Park, S. ; Reagan, W. J. ; Goldstein, R. ; Zhong, S. ; Lawton, M. ; Rajamohan, F. ; Qian, K. ; Liu, L. and Gong, D.W. (2009). Alanine Aminotransferase Isoenzymes: Molecular Cloning and Quantitative Analysis Of Tissue Expression In Rats and Serum Hepatology. , 49: 598–607.
[33]Teppala S. Shankar A. Li J. Wong T. Ducatman A. (2010) Association between Serum γ-Glutamyltransferase and Chronic Kidney Disease among US Adults. Kidney Blood Press Res. 33:1–6.
[34]Tietz, N.W.; Burtis, C.A. and Ashwood, E.R. (1999). "Text Book Of Clinical Chemistry", W.B. Saunders Company, Philadelphia., 3rd Ed. , P. 809-857.
[35]Valeria A., Alessia T., Aldo P., Renata B., Maria F., Riecardo B., Cecilia V., Alfonso P. and Emilia B. (2009). Akinetic study of gamma glutamyl transferase (GGT) – mediated S-nitrosoglutathione catabolism Archives of Biochemistry and Biophysics,481;p-191-196. | ||
|
Statistics Article View: 526 PDF Download: 521 |
||