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Synthesis and Characterization of Some New Oxazolidinone and Thiazolidinone Derivatives Via Reaction of Schiff Bases Derived from some Amino Acids | ||
| Journal of University of Anbar for Pure Science | ||
| Article 18, Volume 11, Issue 3, 2017, Pages 69-76 PDF (1.11 M) | ||
| Document Type: Research Paper | ||
| DOI: 10.37652/juaps.2017.145551 | ||
| Authors | ||
| Hajer H. Abbas; Obaid H. Abed | ||
| University of Anbar – college of Education for pure science | ||
| Abstract | ||
| New derivatives of 2,3- substituted – oxazolidinone and thiazolidinone were synthesized by cycloaddition reaction of glycolic acid and thioglycolic to various Schiff bases derived from some commercially available amino acids in anhydrous 1,4-dioxane under dry and reflux conditions. Schiff's bases were synthesized by refluxing various amino acids with aromatic aldehydes and ketones with few drops of glacial acetic acid as a catalyst in absolute methanol. The products were isolated, purified and characterized by their melting point , FT-IR and 1HNMR spectra and C.H.N analysis. | ||
| Keywords | ||
| Oxazolidinone; Thiazolidinone; Glycolic acid; Thioglycolic; Imines | ||
| References | ||
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