- All Journals
- Al-Qadisiyah University
- Basrah University
- Kirkuk University
- Mosul University
- The Iraqi Borad for Medical Specialization
- University of Anbar
- University of Technology
- Al Mustafa University
- Al-Zahraa University for Women
- Alnoor University
- Kunooz University
- Misan University
- Ninevah University
- Tikrit University
- University of Al-Hamdaniya
- University of Kerbala
Novel Analytical Method For The Determination Of Atenolol In Pharmaceutical Preparations | ||
| journal of the college of basic education | ||
| Article 1, Volume 12, Issue 58, 2009, Pages 49-57 | ||
| Authors | ||
| H. Al-kahdimy; Abass S; Ahmed A. Hussain Al-Amiry; Raghida E. Wagie; Huda A. Hussain | ||
| Abstract | ||
| An accurate, and sensitive novel method was designated chemically for the determination of atenolol in pharmaceutical drugs. The complex formation between copper(II) and atenolol was studied both in aqueous and methanolic media. Complex formation depend on reaction conditions at different metal-to-ligand molar ratios. The mononuclear violet complex cation Cu(Atenolol)4+2 contains two ligands in an anionic bidentate form (through the hydroxyl oxygen and amino nitrogen) and two in a neutral form bound monodentately with an distorted octahedral geometry. The new analatical method based on measuring absorbance in UV-visible at λmax 350nm. Optimum pH and divalent copper ion concentration were estimated. Linearity(40-250), detection limit 07*10-7M. were determined. The complex is identified with UV-visible and IR spectra. The molar ratio also investigated and found 1:4(Cu:Atn). | ||
|
Statistics Article View: 19 PDF Download: 10 |
||