Histological study of the effect of eucalyptol oil vapours on the development of the palate and tooth germ (experimental study on rats)

Y. Al- Hijazi, Athraa; T. Jehad, Muhanad

	Histological study of the effect of eucalyptol oil vapours on the development of the palate and tooth germ (experimental study on rats)
Journal of baghdad college of dentistry
Article 1, Volume 23, Issue 3, 2011, Pages 61-66
Authors
Athraa Y. Al- Hijazi; Muhanad T. Jehad
Abstract
ABSTRACTBackground: Eucalyptol is a natural organic compound. The aim of this study was to evaluate the effect of theeucalyptol oil vapour on the palate and tooth germ development of rats embryos for the periods of (16th day ,18th dayintrauterine life and one day old rats) histologically and histomorphometrically.Materials and Methods: In this study thirty pregnant albino Wistar female rats(2-3 months of age, 200-250 gm of weight)were divided into two groups: Control group not subjected to the synthetic eucalyptol oil inhalation vapour andexperimental group subjected to the synthetic eucalyptol oil inhalation vapour. The embryos at 16,18 day of intrauterinelife and one day old were histologically studied for the development of palate and molar tooth germ development.Results: The results demonstrated a retardation of the palate and tooth germ development of 16th and 18th intrauterinelife embryos of experimental groups in comparison to control. Immature enamel , wide predentin and interglobulardentin were detected in the tooth germ of embryo (one day old) from pregnant rats exposed to the eucalyptol oilvapour.Conclusions : Eucalyptol oil vapour can affect on the palate(Failure of fusion of palatine shelves) and tooth germdevelopment (mineralization and maturation process of dentin and enamel respectively showing immature enameland interglobular dentin with wide predentin ) .Key words: Eucalyptol oil, Wistar rats, palate , molar tooth germ, palatine shelves. (J Bagh Coll Dentistry 2011;23(3): 61-66).

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