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EFFECT OF COPPER ON SOME SERUM BIOCHEMICAL VARIABLES IN MALE ALBINO RATS. | ||
| Journal of University of Anbar for Pure Science | ||
| Article 7, Volume 5, Issue 1, 2011, Pages 17-24 PDF (411.84 K) | ||
| Document Type: Research Paper | ||
| DOI: 10.37652/juaps.2011.15498 | ||
| Author | ||
| HANADI A. ABDUL-RAZZAQ ALDARAJI* | ||
| Anbar University - College of Education for Pure Sciences | ||
| Abstract | ||
| The effect of copper on some serum biochemical measurements was tested in rats including some of the key enzymes such as Alkaline phosphatase (ALP) and Acid phosphatase (ACP) and Aspartate Aminotransferase (AST) and Alanine Aminotransferase (ALT) and Lactate Dehydrogenase (LDH) and Glucose - 6 - phosphate Dehydrogenase (G6PDH), in addition to measuring of total protein . These biochemical measurements tested for each group of male rats , treatment and control results showed significant changes in enzymatic activity and total protein compared to the control group , where it was observed a significant decrease in the amount of total protein (P<0.05) compared with a control , where the greater concentration of copper increased with low amount of total protein . It was also observed a significant decrease (P<0.05) in the effectiveness of the enzyme Alkaline phosphatase (ALP) concentrations in all treatment of male rats compared with control group. The enzyme Acid phosphatase (ACP) was the cause of copper increased significantly (P<0.05) in the effectiveness of this enzyme in all the different concentrations of copper as compared to control . In the enzymes of the Aspartate Aminotransferase (AST) and Alanine Aminotransferase (ALT) , where it was noted that increased significantly (P<0.05) in the effectiveness of the enzyme (AST) compared to control and decrease significantly (P<0.05) the level of effectiveness of the enzyme (ALT) compared to control . In the enzyme Lactate dehydrogenase (LDH) has been observed a significant decrease (P<0.05) as compared to the enzyme effectively control the three transactions as a result of a copper . In the enzyme Glucose – 6 - phosphate Dehydrogenase (G6PDH) , it was noted that increased significantly (P<0.05) in the effectiveness of the enzyme as a result of exposure to different concentrations of copper as compared to control . | ||
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