ABD KHADOM, M. (2012). PREPARTION OF SOME NEW COUMARIN DERIVATIVES WITH MEASURING BIOLOGICAL ACTIVITY. , 1(3), 52-57. doi: 10.37652/juaps.2007.15571
MUHAMMED ABD KHADOM. "PREPARTION OF SOME NEW COUMARIN DERIVATIVES WITH MEASURING BIOLOGICAL ACTIVITY". , 1, 3, 2012, 52-57. doi: 10.37652/juaps.2007.15571
ABD KHADOM, M. (2012). 'PREPARTION OF SOME NEW COUMARIN DERIVATIVES WITH MEASURING BIOLOGICAL ACTIVITY', , 1(3), pp. 52-57. doi: 10.37652/juaps.2007.15571
ABD KHADOM, M. PREPARTION OF SOME NEW COUMARIN DERIVATIVES WITH MEASURING BIOLOGICAL ACTIVITY. , 2012; 1(3): 52-57. doi: 10.37652/juaps.2007.15571

PREPARTION OF SOME NEW COUMARIN DERIVATIVES WITH MEASURING BIOLOGICAL ACTIVITY

Journal of University of Anbar for Pure Science
Article 14, Volume 1, Issue 3, 2007, Pages 52-57    PDF (352.76 K)
Document Type: Research Paper
DOI: 10.37652/juaps.2007.15571
Author
MUHAMMED ABD KHADOM*
Department of Chemistry - College of Education - University of Anbar
Abstract
The present study was designed to be into stages. The first stage included preparing and dignosing four compounds of Schiff's-bases throught condensing be town 3-amino coumarin (1) with aldehyde aromatic. While, the second stage included the reaction the prepared Schiff's-bases (2a-d)with the compound 4-hydroxy coumarin and the compounds produced(3a-d). The biological effects of the prepared compounds towards some positive bacteria Gram and negative Gram studied Staphylococcus aureu, Bacillus subtilis, Bacillus cereus, Psedomonase aeruginosa,. Also towards some fungi including Aspergllus niger, penicillium italicum, fusarium oxysporum.
Keywords
PREPARTION; Coumarin; biological activity
References
  1. H-Schiff.Ann.,(1864). 131,118.
  2. A.A.H. Saeed,(1968). Condenation of Ethyl N-Arylformimidates with phenols and Arylsul Fony hydrazides., M.Sc. thesis, unive. Of Baghdad.
  3. L.,Reav Voinov I., Ivanove E. and Popov D. (1990), Antitumor activity of som coumarin derivatives, pharmazie., 45: 696: Chem.. Abstr., 114, 74711 B.
  4. Z. Nofal M., EL-Zahar M. and Abd ELKarim S. (2000), Novel coumarin derivative with expected biological activity, Molecules, 5: 99-113.
  5. M., EL-Agrod Abd, EL-Latif M. S., ELHady N. A., Fakery A. H. and Bedair A. H. (2001), Hetroaromatisation with 4-hydroxy coumarin part 2, Molecules , 6, 516-527.
  6. S. Pratibha and Shreeya P. (1999), synthesis Characteriztion, Indian J. Chem. 38B, 1139-1142.
  7. T. ,Patonay Litkei G. Y., Bognar R., Erdei J. and Misztic C. (1984), Synthesis antibacterial and antifungal activity of 4-hydroxy- coumarin derivatives, Analogues of Novobiocin, Pharmazie, 39: 2, 86-91.
  8. R. M., Shaker (1996), Synthesis and reaction of som new 4H-pyrano[3,2-c]benzopyran-5-one derivative and their potential biological activity, Pharmazie, 51,148.
  9. F., EL-Farargy (1991), Synthesis and some reaction of 8-teri-butyl-6-hydroxy-4-methyl coumarin, Egypt J. Pharm. Sci., 32 ,625.
  10. Manolov and Danchev N. D., (1995), Synthesis toxicological and pharmacological assessment of some 4-hydroxy coumarin, Eur.J. Med Chem. Chim. Ther., 30:6, 531-536.
  11. A., Emmanuel-Giota Fylaktakidou K. C. Hadjipavlou-Litina D. J., Litinas K. E. and nicolaides D. N., (2001), Synthesis and biological evolution of  several 3-( coumarin-4-yl)titrahydroisoxazole and 3-(coumarin-4-yl)dihydropyrazole derivative, J, Hetrocyclic Chem., 38:3, 717-722.
  12. R. O. Kennedy and Thomes R. D., (1997), Counarins: Biology Applications and Mode of Action, Wiley and Sons.
  13. M. Zahradnik (1992), The Production of Fluorescent Brightening Agent, Wiley and Sons.
  14. S. Srirupa and Versha S., (1989), Studies on 3-aminoV derivatives as potent antifungal and antibacterial agents, J. Chem. Soc, 66 : 166-168.
  15. A.,  Kumar Verma M., Saean A. K. and Shanker K., (1987), Synthesis of 3-(α-arylazobenssylideneamino/furfurylideneamino) coumarin and their anti-inflammatory activity, Indian J. Chem., 26B: 1-12, 378-380.
  16. D. Chakravarti and Das R., (1971), Synthesis of 3-substuted coumarin . part 1, 48: 4, 371.
  17. M. A., Al-Haiza (2002), Reaction with 6-phenyl-2- -thiouracil preparation of subtitled and fused pyrimidines, J. Saudi Chem. Soc., 6: 1, 71-82.
  18. Y. L., Nene and Thapliyal P. N., (1982), fungicides in Plant disease control, Oxford and IBH Publ. New Delhi, P. 192.
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