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Oxidative Stress in Patients with Rheumatoid Arthritis | ||
| Mosul Journal of Nursing | ||
| Article 3, Volume 6, Issue 1, 2018, Pages 17-22 PDF (757.94 K) | ||
| Document Type: Original Articles | ||
| DOI: 10.33899/mjn.2018.160078 | ||
| Authors | ||
| Amina Hisham Mohammed1; Kassim Salih Abdullah Al Neaimy* 2 | ||
| 1MSc, University of Mosul, College of Medicine, Department of Pharmacy, | ||
| 2PhD , Mosul University, College of Medicine Department of Pharmacology E-mail:[email protected]: 009647701676407 | ||
| Abstract | ||
| Background: There is a relationship between oxidative stress and rheumatoid arthritis. Objective: to assess total antioxidant status by measurement of total antioxidants status, and oxidative stress by measurement malondialdehyde, in patients with. Design: case -control study. Setting: referred patients from private clinics . Methodology: The study was conducted on patients referred from private clinics of rheumatology. The period between Nov.1st 2017 and Jun. 1st 2008. thirty four female with rheumatoid Arthritis , and thirty, sex and age-matched healthy volunteers as control group participated in the study. Total antioxidants status and malondialdehyde were measured in both groups. Results: rheumatoid Arthritis patients have lower total antioxidants status values than that of the control group (0.94±0.24 and 1.95±0.20 respectively) (P value <0.0001). The malondialdehyde values was higher in patients group than control group (1.34±0.42 and 0.88±0.26 respectively) (P value <0.0001). Conclusion: rheumatoid Arthritis patients have decreased level of total antioxidants status and increased level of malondialdehyde than the control group . | ||
| Keywords | ||
| Antioxidant status; oxidative stress; Rheumatoid arthritis | ||
| References | ||
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