Salivary enzymes as markers of chronic periodontitis among smokers and non smokers

N. Mohammad, Ayser

	Salivary enzymes as markers of chronic periodontitis among smokers and non smokers
Journal of baghdad college of dentistry
Article 1, Volume 23, Issue 3, 2011, Pages 83-87
Author
Ayser N. Mohammad
Abstract
ABSTRACTBackground: the periodontal cells contain many intra cellular enzymes like alanine aminotransferase (ALT). asparateaminotransferase (AST), and lactate dehydrogenates (LDH) that are released outside into the saliva and gingivalcrivicular fluid (GCF) after destruction of periodontal tissue during periodontitis.Aim of the study: To determine the activity of these enzymes in saliva among smoker and non smoker patients withchronic periodontitis, and its relation to the clinical periodontal parameters (plaque index PLI, gingival index GI,pocket depth PD and clinical attachment level CAL).Material & methods: 40 samples of chronic periodontitis patients (20) non smokers and (20) smokers were collectedfor the study of salivary (AST), (ALT), and (LDH) levels were analyzed spectra metrically.Result: statistical analysis revealed highly significant difference in LDH activity (142±14.63IU/L) between smoker andnon smoker groups with significant positive correlation between the activity of LDH and GI, PD and CAL amongsmokers. Also significant positive correlation between AST, ALT, LDH enzymes and CAL in smokers.Conclusion: The present study showed a significant positive correlation between CAL and all enzymes levels amongsmokers.Key words: non smokers, smokers, salivary enzymes, periodontitis. (J Bagh Coll Dentistry 2011;23(3): 83-87).

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