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N-terminal Pro-brain Natriuretic Peptide in Apparently Healthy Smokers. | ||
| Al-Qadisiah Medical Journal | ||
| Article 1, Volume 13, Issue 1, 2017, Pages 58-62 PDF (0 K) | ||
| Authors | ||
| Seenaa Badr Mohammed; Zainab Falah Hassan; Thanaa Mohammed Juda; Maan Abdulameer Kitab; Zinah abbass ali | ||
| Abstract | ||
| Background and objective Smoking is a major cause of cardiovascular diseases. N-terminal pro-B-type natriuretic peptide (NT-proBNP) is a valid negative biomarker of left ventricular (Lv) dysfunction. The current study investigated whether smoking has an effect on NT-proBNP serum level. Methods: A total of 44subjects 22smokers and 22 non smokers as controls were enrolled in the study. History of cardiovascular or pulmonary disease was an exclusion criterion. Serum levels of NT-proBNP were measured using an enzyme linked immunosorbent assay. Results: Analysis of data showed that there was a significant difference (P < 0.05, in serum NT-proBNP between smokers and controls.proBNP were 410 and 111 pg/ml in smokers and controls, respectively. Also, serum NT-proBNP level correlated with both average number of daily cigarettes smoked and body mass index of smokers. Conclusion These results showed that smoking could increase serum levels of NT-proBNP. Accordingly, an elevated NT-proBNP could be a strong predictor of Left ventricular dysfunction in smokers | ||
| Keywords | ||
| terminal pro; brain natriuretic peptide; smoking; BMI; numbers of cigarettes | ||
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