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Preparation, Characterization and Biological Activity of New Nickel(II) Complexes Containing Mixed Ligands | ||
| Journal of Education and Science | ||
| Article 12, Volume 20, Issue 2, 2007, Pages 105-115 PDF (5.2 M) | ||
| Document Type: Research Paper | ||
| DOI: 10.33899/edusj.2007.162824 | ||
| Authors | ||
| Zuhoor Dawood; Adeeba Shareef | ||
| Abstract | ||
| Nickel(II) complexes containing mixed ligands; semicarbazone (SCH) {benzaldehyde semicarbazone (BSCH) or 2-fluorobenzaldehyde semicarbazone (FSCH)} and salicylaldehyde (SH) or anthranilic acid (AH) or 2- \ methylaminofuran (FH) have been prepared and characterized physicochemically. Complexes of the type [Ni(SCH)(LH)2](N03)2 {where SCH = BSCH or FSCH, LH = SH or AH or FH} have been proposed . The biological activities of the resulted complexes have been evaluated by agar plate diffution technique against five human pathogenic bacterial strains: Bacillus subtilis, Streptococcus pyogenes, Staphylococcus aureus, Pseudomonas aeruginosa and Proteus vulgaris. The complexes were found to have antimicrobial activity on some gram-positive and gram-negative bacteria, in vitro. The effective concentrations ranging between 31.25-500 J.lg/ml. Pseudomonas aeruginosa and Staphylococcus aureus were the most sensitive bacteria followed by Proteus vulgaris. | ||
| Keywords | ||
| biological activity; New Nickel(II); Streptococcus pyogenes | ||
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