Reverse Injection Enthalpimetric Technique for the Determination of Cerium(IV) and Sulpha Drugs

Zewar, Sardir; M.Abdulla, Ahmad; M.Najib, Fadhil

	Reverse Injection Enthalpimetric Technique for the Determination of Cerium(IV) and Sulpha Drugs
Iraqi National Journal Of Chemistry
Article 1, Volume 0, Issue 26, 2014, Pages 251-262
Authors
Sardir Zewar; Ahmad M.Abdulla; Fadhil M.Najib
Abstract
Abstract The new thermometric sensor developed by the present authors and appeared in (Talanta, 2007, 71(1),141-148) has been subjected to further applications. In this work Ce(IV) has been determined using Reverse Injection Enthalpimetry (RIE) , in which the analyte Ce(IV) was added to excess reagent (sulphanilic acid). For the determination of (4 - 35 μg.mL-1) Ce(IV) in the final solution, a fixed volume between (0.1 – 0.8)mL. analyte present in . (0.5 M H2SO4), was injected into an excess of sulphanilic acid (20 ml. 1.25x10-2M) in the thermometric cell. Only one blank of 0.5 ml.(0.5 M H2SO4) was performed and its value was subtracted from all the results. The calibration curve was linear with R2 = 0.999 with a recovery between 96 – 101% with precision of about 2%, and t-test showed no significant difference between the true value and the mean at 95% confidence limit, indicating good validity of the method. The above procedure was reversed for the determination of sulphanilic acid and some sulpha drugs. In this case a portion of 0.5 mL. of the analyte or the standard containing not less than 10mg of sulphanilic acid or the sulpha–drug is injected into an excess of Ce(IV) as a reagent in the thermometric cell and the procedure will be continued.
Keywords
cerium; Reverse Injection Enthalpimetry

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