Effect of some Materials and Drugs on Entamoeba gingivalis Culture

Younes, Khansaa A.; Taqa, Ghada A.; Nayef, Najah S.

doi:10.33899/rjs.2019.163300

	Effect of some Materials and Drugs on Entamoeba gingivalis Culture
Rafidain Journal of Science
Article 11, Volume 28, Issue 4, 2019, Pages 40-49 PDF (432.47 K)
Document Type: Research Paper
DOI: 10.33899/rjs.2019.163300
Authors
Khansaa A. Younes^* ¹; Ghada A. Taqa¹; Najah S. Nayef²
¹Department of Dental Basic Sciences College of Dentistry/University of Mosul
²Department of Biology College of Science/University of Mosul
Abstract
The aim of this study was to investigate the effects of some materials and drugs on Entamoeba gingivalis culture which was isolated from gums in gingivitis patients who attended to the periodental disease department at the college of Dentistry/ Mosul University, at the period from August to October 2018. Five different concentrations of Flagyl, Ketamine, Bowsella and Apignein were prepared then added to the culture media of the parasite at three periods (2, 4, 6) hours. as (0.0001, 0.0002, 0.0004, 0.0008, 0.0016) microgram/ml. Statistical analysis showed that there were significant difference between concentrations and time which showed that best concentrations were 0.0016 mg/ml for Flagyl, Ketamine, Apignein which inhibit parasite growth as (0.0, 4.73j, 9.53g) respectively also reduced parasite survival rate at (100%, 72.81%, 54.4%) respectively in the time period at (6 hours) while Bowsella at 0.0008 mg/ml inhibition of parasite growth to (5.47l) also reduced parasite survival rate to (72.04%) compared together concentrations and time periods (2, 4) hours which showed slight differences between them.
Keywords
Entamoeba gingivalis; Flagyl; Apignin; Ketamine; gingivitis

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