PROPHYLACTIC TRANEXAMIC ACID VERSUS AUTOLOGOUS BLOOD TRANSFUSION TO REDUCE BLEEDING IN ELECTIVE CORONARY BYPASS GRAFT SURGERY

Abdulmajeed, Othman Ismat

doi:10.33762/bsurg.2019.163859

	PROPHYLACTIC TRANEXAMIC ACID VERSUS AUTOLOGOUS BLOOD TRANSFUSION TO REDUCE BLEEDING IN ELECTIVE CORONARY BYPASS GRAFT SURGERY
Basrah Journal of Surgery
Article 6, Volume 25, Issue 1, 2019, Pages 27-31 PDF (130.78 K)
Document Type: Research Paper
DOI: 10.33762/bsurg.2019.163859
Author
Othman Ismat Abdulmajeed
College of Medicine, Hawler Medical University, Erbil, IRAQ
Abstract
Abstract Many blood conservation strategies were developed in the past decades to reduce risk of bleeding and the need for blood products among patients undergoing cardiac surgeries. This study was conducted to define the benefit of reinfusion of preoperative collected autologous blood in reduction of the risk of bleeding and the need for blood and blood products in comparison with tranexamic acid. This single centre single-blinded, randomized study was conducted in Erbil cardiac centre during the period from 1st of November 2018 to 30th of April 2019. A total of 150 patients were divided into three groups with 50 patients for each. The 1st group received nothing, the 2nd group received initially infusion of 200mg/hr of tranexamic acid until reaching 1.5gm/hr, and the 3rd group received one pint of preoperative auto-transfused whole blood. Data on risk of bleeding and the need for blood and blood products were collected using special questionnaire prepared for the reason of this study and were analyzed using appropriate statistical tests. Patients receiving autologous blood showed lower chest tube drainage than the other study groups with a p value of

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