MULTINODULAR GOITER AND RISK OF MALIGNANCY, SURGERY OR FOLLOW UP ?

Alwajeeh, Ali Yousif

doi:10.33762/bsurg.2019.163874

	MULTINODULAR GOITER AND RISK OF MALIGNANCY, SURGERY OR FOLLOW UP ?
Basrah Journal of Surgery
Article 12, Volume 25, Issue 1, 2019, Pages 61-65 PDF (132.3 K)
Document Type: Research Paper
DOI: 10.33762/bsurg.2019.163874
Author
Ali Yousif Alwajeeh
General Surgeon, Almawanee Teaching Hospital, Basrah, IRAQ.
Abstract
MULTINODULAR GOITER AND RISK OF MALIGNANCY, SURGERY OR FOLLOW UP ? Ali Yousif Alwajeeh@ & Abutalib Bader Al Luaibi* @MB,ChB, CABS, Consultant General Surgeon. MB,ChB, FIBMS, General Surgeon, Almawanee Teaching Hospital, Basrah, IRAQ. Abstract Nodular goiter is one of the most common presentation of thyroid gland diseases. The risk of development of thyroid cancer is relatively rare (1%) of all types of tumors, however, it is the most common endocrine malignancy, and usually presented as multinodular goiter. Fine needle aspiration cytology (FNAC) considered as the golden tool in the diagnosis of thyroid nodule though, it still has false negative rate which is variable depending on the experience and the technique being used. This means that even if the FNAC done prior to surgery shows negative finding, this doesn't exclude the presence of carcinoma, especially in multinodular goiter where it is possible not to sample the involved area. In this prospective study which was done in Almawanee Teaching Hospital between 2012-2018, 69 patients with Multinodular goiter where considered for the risk of harboring an incidental malignancy. The results of patients with multinodular goiter of benign origin was 57 patients (82.86%) while multinodular goiter which has an incidental malignancy was 12 patients (17.14%). Conclusion: due to relatively high risk of malignancy in multinodular goiter especially with noncompliance for follow-up from patients and risk of missing incidental malignancy by FNAC in multinodular goiter, it is preferable to do total or near total thyroidectomy. Key words: Goiter, Malignancy, FNAC, Surgery, Incidence
Keywords
Goiter; malignancy; FNAC; surgery; Incidence

References
1. Shrestha D, Shrestha S. The incidence of Thyroid Carcinoma in Multinodular Goiter. Journal of college of medical science-Nepal, 2014, 10(4); 18-21. 2. Pang H-N, Chen C-M. Incidence of Cancer in nodular goiter. Ann Acad Med Singapore, 2007, 36; 241-43. 3. Hanumanthappa M.B., Gopinathan S., Rithin Suvarna. The incidence of Malignancy in Multinodular goiter. Journal of clinical and diagnostic research, 2012, 6(2); 267-70. 4. Ameet V. Khatawkar, Shreeharsha Mallappa Awati. Multinodular goiter: Epidimiology, Etiology, Pathogenesis and Pathology. IAIM, 2015, 2(9); 152-56. 5. Pier Paolo Gandolfi, Antonio Frisina, Maurizio Raffa, Flavia Renda, Alberto Tombolini. The incidence of Carcinoma in multinodular goiter: retrospective analysis. ABMAP, 2004,75; 114- 17. 6. Jie Luo, Catherine mcmanus, Herbert Chen, Rebecca S. Sippel. Are there predictors of malignancy in patient with multinodular goiter?. J Surg Res., 2012, 174(2); 207-10. 7. Mohammad Mostafizur Rahman, Mohammad Idrish, Abdul Karim, Mohammad Shahrior Arafat, Mohammad Hanif. Frequency of malignancy in Multinodular goiter. Bangladish J Otorhinolaryngeal, 2014, 20(2); 75-79. 8. Laszlo Hegedus, Steen J. Bonnema, Finn N Bennedbaek. Management of simple nodular Goiter: Current Status and Future perspectives. Endocrine Review, 2003, 24(1); 102-132. 9. Sharma R., Verma N., Kaushal V., Sharma DR. Diagnostic Accuracy of fine needle aspiration cytology of thyroid Gland lesion: A study of 200 cases in Himalayan belt. J CAN Res Ther, 2017, 13; 451-55. 10. Rozan K. A., William O. Q., Zalooma J. S., Multinodular goiter Epidimiology and Etiology: Retrospective Study. Ger J Thy., 2016, 5(2); 165-70. 11. Smith J. J. Cancer after thyroidectomy: a multi institutional experience with 1,523 patients. J Am Coll Surg, 2013, 216; 571-79. 12. Ullah I., Hafeez M., Ahmad N., Muhammad G., Gandapur S. Incidence of thyroid malignancy in multinodular goiter. J Med Sci., 2014, 22(4); 164-65. 13. Kuan-Chen Chen, Usama Iqbal, Chug-Huei Hsu, Cheng-Ling Huang. The impact of different surgical procedures on hypoparathyroidism after thyroidectomy. Md-journal, 2017, 96; 43-50. 14. Thomusch O, Machens A, Sekulla C. Multivariate analysis of risk factors for postoperative complications in benign goiter surgery: prospective multi-center study in germany. World j surg, 2000, 24; 1335-41.
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