Ukwueze, C., Akpan, E., Ezeokonkwo, R., Nwosuh, C., Anene, B. (2020). Haematological, oxidative stress and electrolyte alterations in puppies with canine parvoviral enteritis. , 34(1), 65-69. doi: 10.33899/ijvs.2019.125582.1094
Chigozie Ukwueze; Ekemini S Akpan; Romanus C Ezeokonkwo; Chika I Nwosuh; Boniface M Anene. "Haematological, oxidative stress and electrolyte alterations in puppies with canine parvoviral enteritis". , 34, 1, 2020, 65-69. doi: 10.33899/ijvs.2019.125582.1094
Ukwueze, C., Akpan, E., Ezeokonkwo, R., Nwosuh, C., Anene, B. (2020). 'Haematological, oxidative stress and electrolyte alterations in puppies with canine parvoviral enteritis', , 34(1), pp. 65-69. doi: 10.33899/ijvs.2019.125582.1094
Ukwueze, C., Akpan, E., Ezeokonkwo, R., Nwosuh, C., Anene, B. Haematological, oxidative stress and electrolyte alterations in puppies with canine parvoviral enteritis. , 2020; 34(1): 65-69. doi: 10.33899/ijvs.2019.125582.1094

Haematological, oxidative stress and electrolyte alterations in puppies with canine parvoviral enteritis

Iraqi Journal of Veterinary Sciences
Article 10, Volume 34, Issue 1, 2020, Pages 65-69    PDF (581.76 K)
Document Type: Research Paper
DOI: 10.33899/ijvs.2019.125582.1094
Authors
Chigozie Ukwueze* 1; Ekemini S Akpan1; Romanus C Ezeokonkwo2; Chika I Nwosuh3; Boniface M Anene4
1Department of Veterinary Medicine, Michael Okpara University of Agriculture, Umudike
2Department of Veterinary Parasitology, University of Nigeria, Nsukka.
3Research Directorate, National Veterinary Research Institute, Vom, Nigeria.
4Department of Veterinary Medicine, University of Nigeria, Nsukka.
Abstract
Haematological changes, oxidative stress markers and electrolyte alterations were evaluated in puppies infected with canine parvovirus type 2 (CPV-2) that were presented to veterinary hospitals and clinics in South Eastern, Nigeria. Fifty-one dogs were used for the study and they were assigned into three groups. Group I consist of 21 diarrhoeic dogs naturally infected with canine parvovirus, groups II, were 15 diarrhoeic dogs uninfected with canine parvovirus and group III, were 15 apparently healthy dogs which served as the control. Immunochromatographic (IC) test was used to screen the dogs for canine parvovirus type 2 infections. The mean red blood cell (RBC) counts, packed cell volume (PCV) and haemoglobin (HB) concentrations were significantly lower in the diarrhoeic infected than diarrhoeic non-infected and the control groups. The mean catalase (CAT) of diarrhoeic non-infected group was significantly lower than diarrhoeic infected group and the control. The mean malondialdehyde (MDA) of both diarrhoeic infected and diarrhoeic non-infected groups were significantly higher than the control. The mean serum sodium (Na+) level of the diarrhoeic non infected group was significantly lower than the diarrhoeic infected group. The mean serum potassium (K+) level was significantly lower both in diarrhoeic infected and diarrhoeic non-infected groups compared to the control groups. It was therefore concluded that the levels of oxidative stress and electrolyte alterations may not be affected by the origin or aetiology of a disease (CPV-2), but on the severity of the infection.
Keywords
CPV-2; Haematology; oxidative stress; Electrolytes alterations; dogs
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