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Green Chemistry Synthesis of Five-Membered Heterocylic Derivatives (1, 3, 4-oxadizoles) by Using Grinding Technique | ||
| Kirkuk Journal of Science | ||
| Article 1, Volume 13, Issue 3, 2018, Pages 109-125 PDF (0 K) | ||
| Document Type: Research Paper | ||
| DOI: 10.32894/kujss.2018.164237 | ||
| Authors | ||
| Nihad Ismael Taha* ; Eehab Malik Rasheed | ||
| Department of Chemistry, College of Science, Kirkuk University, Kirkuk, Iraq. | ||
| Abstract | ||
| In this research we prepared about 28 derivatives of five-membered heterocyclic compounds (1,3,4-oxadizoles) in two lines , in the first line we used phenylhydrazide and in the second line we used 4-hydroxy phenylhydrazide as starting material for cyclization, By using eco–friendly efficient synthesis of oxadiazole derivatives through the reaction of aromatic hydrazide with different substituted aromatic aldehydes by grinding them in the presence of catalytical amounts of iodine. | ||
| Keywords | ||
| oxadiazole; Green chemistry; aromatic hydrazide; grinding | ||
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