J. M. Hussan, M., B. Dikran, S. (2009). First- and Second-Order Derivative Spectrophotometryfor Individual and Simultaneous Determination of amoxicillin and cephalexin. , 0(34), 260-269.
Mohammed J. M. Hussan; Sarmad B. Dikran. "First- and Second-Order Derivative Spectrophotometryfor Individual and Simultaneous Determination of amoxicillin and cephalexin". , 0, 34, 2009, 260-269.
J. M. Hussan, M., B. Dikran, S. (2009). 'First- and Second-Order Derivative Spectrophotometryfor Individual and Simultaneous Determination of amoxicillin and cephalexin', , 0(34), pp. 260-269.
J. M. Hussan, M., B. Dikran, S. First- and Second-Order Derivative Spectrophotometryfor Individual and Simultaneous Determination of amoxicillin and cephalexin. , 2009; 0(34): 260-269.

First- and Second-Order Derivative Spectrophotometryfor Individual and Simultaneous Determination of amoxicillin and cephalexin

Iraqi National Journal Of Chemistry
Article 1, Volume 0, Issue 34, 2014, Pages 260-269
Authors
Mohammed J. M. Hussan; Sarmad B. Dikran
Abstract
Abstract
A new spectrophotometric method for individual and simultaneous determination of amoxicillin and cephalexin depending on the first and second derivative mode techniques. The first and second derivative spectra of these compounds permitted individual and simultaneous determination of amoxicillin and cephalexin in concentration interval of (10 – 60μg.ml-1) by measuring the amplitude of peak-to-base line, zero cross at certain wavelengths and the area under peak at selected spectrum intervals. The methods showed reasonable precisionand accuracy and have been applied to determine amoxicillin and cephalexin in four different pharmaceutical preparations.
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