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Effect of Some Biochemical Parameters as Antioxidants in Placenta of infected Pregnant Weman with Toxoplasmosis | ||
| Journal of Education and Science | ||
| Article 5, Volume 29, Issue 3, 2020, Pages 58-67 PDF (417.95 K) | ||
| Document Type: Research Paper | ||
| DOI: 10.33899/edusj.2020.126095.1037 | ||
| Authors | ||
| muna ismail Ibraheem* 1; Layla Abdullah Mustafa2; Ahmed yahya Ismeel3 | ||
| 1دائرة البحوث الزراعیة | ||
| 2Dept.Chemistry, Faculty of Science, University of Mosul | ||
| 3Department of Biochemistry, College of Veterinary Science, University of Mosul | ||
| Abstract | ||
| . Reregulation of biochemical profile of host as a result of host cells-pathogen interaction may involve in pathogenesis of toxoplasmosis disease. The biochemical parameters in the placenta of Toxoplasma-infected pregnant women and non-infected pregnant women (control group) were investigated The criteria taken into consideration are: Superoxide dismutase (SOD) , Peroxidase (Px) , Glutathione- S- transferase (GST) , Lactate dehydrogenase (LDH) , Aryl esterase (AE) , Acetylcholine esterase (AchE) , Vitamin A,C and E As well as placental electrolytes including: Sodium (Na+) , Potassium (K+) , Chloride (Cl-) , Calcium (Ca++) , Selenium (Se) , Cupper (Cu) , Zinc (Zn) , Iron (Fe) , Magnesium (Mg) and Manganese (Mn). The results showed: a non-significant increase in the activity of SOD, GST, LDH and AchE during 6-9 months, and activity of AE during 1-3 months, were determined whereas the activity of Px was decreased in all periods of pregnancyA non- significant increase in the level of vitamin E and non-significant decrease in levels of vitamin A and C during pregnancy periods in placentae of infected pregnant Were observed. . A significant increase (p≤0.01) in levels of Na+ and K+ during 1-3 months and Ca++ during 3-6 months, whereas the level of Cl- decreased during pregnancy periods. A significant increase (p≤0.01) in levels of Seand Mg during 6-9 months and a non- significant increase in level of Cu during 1-3 months and 6-9 months, whereas the level of Zn, Fe and Mn significantly decreased in all periods of Pregnancy in placenta infected women. | ||
| Keywords | ||
| Toxoplasmosis,,; ,،,؛Placenta,,; ,،,؛Vitamins,,; ,،,؛Enzymes,,; ,،,؛Trace elements | ||
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