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Association of Autoimmunity and Parvovirus B19 Infection among Spontaneous Miscarriage Women in Erbil / Iraq | ||
| Rafidain Journal of Science | ||
| Article 4, Volume 29, Issue 1, 2020, Pages 29-38 PDF (515.68 K) | ||
| Document Type: Research Paper | ||
| DOI: 10.33899/rjs.2020.164472 | ||
| Author | ||
| Nyan J. Mohammed* | ||
| Department of Pathological Analysis /College of Science/ University of Knowledge | ||
| Abstract | ||
| The study was conducted from January 2016 to January 2017 at Maternity Teaching Hospital in Erbil city/ Iraq. One hundred and forty women who experienced spontaneous abortions were selected according to inclusion and exclusion criteria and forty normal pregnant women as a control group. Serum from patients and control group subjected for assessment of anticardiolipin IgM, antiphospholipid IgM, Parvovirus B19 IgG and IgM using enzyme linked immune-sorbent assay technique. Prevalence of positive Parvovirus B19 IgG and IgM, anticardiolipin IgM and antiphospholipid IgM, in aborted women was higher than that observed in non-aborted women (control group). Women with the highest frequency of spontaneous abortion found at age group 27–34 year. More frequent of previous spontaneous abortion was 1-2 abortion at the 1st trimester of gestational period. Anticardiolipin antibody and antiphospholipid antibody production trigged by viral infection, and have role in spontaneous abortion in pregnant women. | ||
| Keywords | ||
| Parvovirus Infections; ELISA; Anticardiolipin; Antiphospholipid; Autoimmunity | ||
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