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Effect of Gamma Knife Radiosurgery in Meningioma | ||
| Iraqi Postgraduate Medical Journal | ||
| Article 1, Volume 18, Issue 2, 2019, Pages 107-114 PDF (0 K) | ||
| Authors | ||
| Abdulameer Jasim Al-khafaji; Zaid Sameer Naji | ||
| Abstract | ||
| ABSTRACT: BACKGROUND: Meningioma is a common disease affects middle age patients especially females. Surgery is the first choice of treatment, gamma knife usually is a treatment for residual tumor or sometimes initially when surgery is risky. OBJECTIVE: To evaluate the short time effectiveness of gamma knife in treatment of meningioma with associated complications including necrosis and edema and assessing factors that favor success PATIENTS AND METHODS: A retrospective study from April 2017 to October 2017 in Neurosciences hospital of 35 patients, 25 female and 10 male, age range 36-70 years, brain MRI done before and 6 months after gamma knife, patients evaluated regarding type of meningioma, number of shots, edema and radiation dose RESULTS: The most common types were parasagittal and convexity meningioma, size of tumors ranged from 10mm to 57mm most tumors were 20-29mm, post-gamma necrosis was higher in non-basal meningioma (76.5%) than basal meningioma (44.4%). Necrosis appeared 100% when using > 18 Grey. The necrosis decreased when using doses 14-16 Grey and 10-12 Grey. Non-basal meningioma showed high edema (47.1%) while basal showed less edema (38.9%), higher doses of radiation associated with more edema. Headache improved post-gamma. CONCLUSIONS: Gamma knife is effective and safe option to treat meningioma when surgery is risky, the tumor necrosis is highest in non-basal meningioma and when the dose above 14 grey and the peritumoral edema was highest also in non-basal meningioma and when the dose of radiation above 18 grey. KEYWORDS: Meningioma, Gamma knife surgery, Stereotactic radiosurgery | ||
| Keywords | ||
| Meningioma; Gamma knife surgery; Stereotactic radiosurgery | ||
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