Results of Minimal Dosage Propranolol in the Management of Infantile Haemangioma

, Ahmed Ibraheim Ismaeel; , Zakaria A. Aarajy; , Nuas Hasab Jaafar; , Ahmed Khalaf Jasim

	Results of Minimal Dosage Propranolol in the Management of Infantile Haemangioma
Iraqi Postgraduate Medical Journal
Article 1, Volume 18, Issue 1, 2019, Pages 10-17 PDF (0 K)
Authors
Ahmed Ibraheim Ismaeel; Zakaria A. Aarajy; Nuas Hasab Jaafar; Ahmed Khalaf Jasim
Abstract
ABSTRACT: BACKGROUND: Infantile haemangioma one of the most common tumour of new borns , a safe and effective treatment options are under ongoing research . OBJECTIVE: The authors show the effectiveness and safety of low dose propranolol as a method for infantile haemangioma treatment . METHOD: In this study twenty- four patients with infantile haemangioma in different anatomical locations were treated with oral propranolol and the result were assessed in a retrospective analysis of the results patients were kept on 0.25 mg/kg/day for one month , then on 0.5mg/kg/day in 2 divided doses for another one month , in the third month the dose will be increased to 1 mg/kg/day in 2 divided doses , then the propranolol were given in a maintenance dose ranging between 1-1.5 mg/kg/day in 2 divided doses according to the clinical response .The duration of treatment ranging from 6-18 months as a small dose increasing over a long time . RESULTS: We had achieved excellent result in most of our patients, with reduction of size and fade of color of hemangioma within 1 month from the initiation of treatment, when we stop the treatment no relapses were noticed during our follow up period after finishing the course. CONCLUSION: Propranolol is one of the safest and most effective treatment options for the infantile haemangioma even in low dose, with lower relapse rates and minimal consecutive side effects and drawbacks.
Keywords
KEYWORDS; infantile; haemangioma

Statistics Article View: 495 PDF Download: 294