Construction of New Coated Carbon Electrodes for Determination of Sildenafil Citrate Drug

Mohammed, Aveen K.; Khaleel, Ali I.; Ahmed, Nawzad N.

doi:10.32894/kujss.2020.15.2.1

	Construction of New Coated Carbon Electrodes for Determination of Sildenafil Citrate Drug
Kirkuk Journal of Science
Article 1, Volume 15, Issue 2, 2020, Pages 1-16 PDF (1.27 M)
Document Type: Research Paper
DOI: 10.32894/kujss.2020.15.2.1
Authors
Aveen K. Mohammed^* ¹; Ali I. Khaleel¹; Nawzad N. Ahmed²
¹Department of Chemistry, College of Science, Tikrit University, Tikrit, Iraq.
²Department of Chemistry, College of Science, Sulaymaniyah University, Sulaymaniyah, Iraq.
Abstract
In this research, new coated carbon electrodes were constructed and used for the determination of Sildenafil citrate (SILC) drug. The electrodes were constructed by preparing ion-pair for (SILC) with phosphotungstic acid (PTA) or phosphomolybdic (PMA) acid using dibutyl phthalate (DBP) as a plasticizer. These electrodes showed good sensitivity towards SILC with linear range of (1.0´10^-⁷-1.0´10^-2) M, correlation coefficient, (0.9990), the life time (120) days, optimum temperature range (23-65) ^oC and optimum pH range (2-5) for both electrodes, limit of detection (5.055´10^-8 and 5.116´10^-8) M, slope (57.29 and 59.10) mV/decadefor SILC-PTA and SILC-PMA electrodes respectively. These electrodes were successfully applied for determination of SILC in pure and pharmaceutical preparation form(tablets) with recovery of not less than 98%.
Keywords
Coated carbon electrode; Sildenafil citrate drug; Potentiometry method

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