Synthesis of Some Heterocyclic Compounds Derived From 2-Amino Benzothiazole

Mahmood, Zainab Muataz; Ahmad, Ahmad Kh.

doi:10.33899/edusj.2020.127562.1087

	Synthesis of Some Heterocyclic Compounds Derived From 2-Amino Benzothiazole
Journal of Education and Science
Article 12, Volume 29, Issue 4, 2020, Pages 193-205 PDF (798.83 K)
Document Type: Research Paper
DOI: 10.33899/edusj.2020.127562.1087
Authors
Zainab Muataz Mahmood^* ¹; Ahmad Kh. Ahmad²
¹وزارة التربیة
²Department of Chemistry, Education College for Pure Sciences, University of Mosul.
Abstract
In this thesis, Anmber of heterocylic compound with five and six memberd, Such as substituted imidazole, triazin and thiazolidine. The N-(1,3-benzothiazol-2-yl)-2-chloro acetamide compound(1) was prepared from the reaction of the compound (2-amino benzothiazole) with chloroacetyl chloride. The product(1) was reacted with thiourea and urea to prepare both (imidazole -2-thione (2) and imidazole -2-one(3)) , respectively. As did compound(1) with thiosemicarbazide and semicarbazide to prepared the two compounds (1,2,4-triazine -3-thione (4) and 1,2,4-triazine -3-one (5)) ,respectively. Also compound(1) with ammonium thiocyanate to prepare the compound thiazolidin -4-one (6). From the reaction of compound(1) with phenyl thiourea attended imidazole -2-thione(7). Also from the reaction of (2-amino benzothiazole) with phthalic anhydride or malic anhydride attended compounds (8) and (9) ,respectively. And by reaction compound(8) or (9) with o-phenylene diamine attended compounds (10) and (11) ,respectively. The synthesized compounds are identified by physical (melting points, colour change) and spectral methods such as (IR, proton-NMR).
Keywords
2-amino benzothiazole; thiazolidine; imidazole

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