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Comparison of conventional periodontal therapy versus scaling and root planing with subgingival minocycline gel 2% | ||
| Journal of baghdad college of dentistry | ||
| Article 1, Volume 18, Issue 2, 2006, Pages 57-62 | ||
| Authors | ||
| ; Kholood A. Al | ||
| Abstract | ||
| ABSTRACTBackground: Alternative regimens using subgingival minocycline plus scaling and root planing (SRP/M) significantly improved clinical attachment (CAL) and reduced probing depth (PD) compared with SRP alone. The purpose of this study was to evaluate clinical and radiographic outcomes in 2 periodontitis cohorts, one receiving conventional periodontal therapy and the other receiving scaling and root planing with multiple doses of subgingival minocyclineMaterials and Method: Moderate to advanced chronic periodontitis patients were concurrently treated with either:(1) scaling and root planing with 4 subgingival doses of minocycline in all ≥ 5mm pockets over a 6 month period (SRP/M) n = 25 patients or (2) conventional therapy 6 month period (SRP n = 25 patients). Clinical and radiographic measurements including (PD), CAL, BOP and interproximal bone height (BH), were analyzed at baseline and 1 year.Results: Baseline clinical and radiographic data were similar between SRP/M and SRP patients. PD showed greater mean improvement in SRP/M (1.1 ± 0.1 versus 0.5 ± 0.1 mm P=0.02) with 25% of subject of SRP/M gaining ≥2mm compared to 4.2% in SRP. The mean loss in bone height and percent subjects losing bone height were less in SRP/M (2.9 ± 0.6 mm) than SRP (3.7 ± 0.7mm) while cross sectional SRP/M data between CAL and BH or PD and CAL were highly correlated, changes over 1 year were not correlated among any of these parameters.Conclusion: Scaling and root planing and subgingival minocycline in experimental sites resulted in more PD reduction and less frequent bone height loss than conventional periodontal treatment alone.Keywords: Root planing, minocycline. (J Bagh Coll Dentistry 2006; 18(2) 57-62) | ||
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