Ali, R., Hussein, A. (2020). Clincopathological Assessment of Cases of Inflammatory Bowel Disease & Other Types of Colitis in Province of Basrah. , 20(2), 102-109. doi: 10.52573/ipmj.2020.168617
Russul Mahmood Ali; Alaa G. Hussein. "Clincopathological Assessment of Cases of Inflammatory Bowel Disease & Other Types of Colitis in Province of Basrah". , 20, 2, 2020, 102-109. doi: 10.52573/ipmj.2020.168617
Ali, R., Hussein, A. (2020). 'Clincopathological Assessment of Cases of Inflammatory Bowel Disease & Other Types of Colitis in Province of Basrah', , 20(2), pp. 102-109. doi: 10.52573/ipmj.2020.168617
Ali, R., Hussein, A. Clincopathological Assessment of Cases of Inflammatory Bowel Disease & Other Types of Colitis in Province of Basrah. , 2020; 20(2): 102-109. doi: 10.52573/ipmj.2020.168617

Clincopathological Assessment of Cases of Inflammatory Bowel Disease & Other Types of Colitis in Province of Basrah

Iraqi Postgraduate Medical Journal
Article 2, Volume 20, Issue 2, 2021, Pages 102-109    PDF (187.83 K)
Document Type: Research Paper
DOI: 10.52573/ipmj.2020.168617
Authors
Russul Mahmood Ali1; Alaa G. Hussein2
1* Dept. of Pathology, Laboratories of Al-Imamain Al-Kadhumain Medical city, Baghdad, Iraq
2Dept. of Pathology and Forensic Medicine, College of Medicine, Al-Nahrain University, Baghdad, Iraq.
Abstract
BACKGROUND:
Inflammatory bowel disease is group of inflammatory disorders of unknown etiology. The main members of this group are ulcerative colitis and Crohn's disease (granulomatous colitis).Histopathologic evaluation of colonoscopic mucosal biopsy remains one of the earliest modalities of investigation in patients which clinically suspected. Any biopsy underwent histopathological diagnosis should be accompanied by endoscopic findings and full clinical history.
OBJECTIVE :
Assessment of colonic biopsies in patients of colitis on the basis of specific histopathological criteria and correlation with clinical and endoscopic presentations.
METHOD :
A Retrospective and prospective study included randomly selected 102 colonic specimens from
January 2016 to June 2018.The clinicopathological parameters including (age of the patients, gender, hematochiza, diarrhea and abdominal pain) obtained from endoscopic reports and correlated with                 the histopathological parameters and sections which revised by a senior pathologist.
RESULTS:
Out of (102) patients in this study; there were 41(40.2%) males and 61(59.8%) females. hematochiza is the main presentation in ulcerative colitis, while abdominal pain is the main presentation in Crohn's disease patients and diarrhea in those with non-specific colitis. Certain parameters can favoring                 the diagnosis of non-specific colitis over inflammatory bowel disease and another set favoring ulcerative colitis over Crohn's disease and vice-versa. This leads in shifting of diagnosis of most of endoscopic biopsies rather than resection biopsies. And there is under diagnosis of cases of non-specific colitis and Crohns disease in comparism to Ulcerative colitis.
CONCLUSION:
Inflammatory bowel diseases are female predominate.Ulcerative Colitis predominate in 3rd and 4th decades of life, Crohn's disease is more in 2nd and 3rd decades while non specific colitis are more
found in old age. Correlation between clinical, endoscopic and histopathological features is essential  in the diagnosis of inflammatory bowel diseases. Accurate diagnosis of inflammatory bowel diseases depends on finding of certain histopathological features.
Keywords
Inflammatory bowel diseases; Ulcerative Colitis; Crohn's disease; histopathological features diagnostic of IBS; granulomatous colitis
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