Preparation and Characterization of Polymer Blend and Nano Composite Materials Based on PMMA Used for Bone Tissue Regeneration

Kadhum Alsaedi, Sally A.; Salih, Sihama I.; Hashim, Fadhil A.

doi:10.30684/etj.v38i4A.383

	Preparation and Characterization of Polymer Blend and Nano Composite Materials Based on PMMA Used for Bone Tissue Regeneration
Engineering and Technology Journal
Article 3, Volume 38, 4A, 2020, Pages 501-509 PDF (786.29 K)
DOI: 10.30684/etj.v38i4A.383
Authors
Sally A. Kadhum Alsaedi^* ¹; Sihama I. Salih^* ¹; Fadhil A. Hashim^* ²
¹Materials Engineering Department, University of Technology, Iraq, Baghdad
²Materials Engineering Department, University of Technology, Iraq, Baghdad.
Abstract
As the elderly population increases, the need for bone loss treatments is increasing. Vital substances used in such treatments are required to continue for a longer period and work more effectively. The particularly important biological material is poly methyl methacrylate (PMMA) bone cement, which is widely used in damaged bone replacement surgery. So, this study focused on the role of added some nanoparticles consist of zirconia (ZrO2), and magnesia (MgO) on the binary polymeric blend (Acrylic bone cement: 15% PMMA) for a bone scaffold. Where, ZrO2 and MgO nanoparticle was added with selected weight percentages (0, 0.5, 1, 1.5 and 2 wt.%), which were added to the polymer blend matrix. Some mechanical properties were studied including the tensile strength and young modulus for all the prepared samples. The chemical bonding of nanoparticles and synthetic binary polymeric blend composites was evaluated by Fourier Transform Infrared (FTIR) spectroscopy. Tensile strength and young modulus of binary polymeric blend reinforced with 1.5 wt.% ZrO2, and 1 wt.% MgO, significantly increased. The surface morphology of the fracture surface of tensile specimens was examined by Scanning electron microscope (SEM). The SEM images confirmed that the homogenous distribution of nanoparticles (ZrO2, and MgO) within the polymeric blend matrix.
Keywords
Acrylic bone cement; PMMA; Tensile Strength; Young’s modulus

References
[1] H. Y. Atay and E. Celi , “Multifunctional polymer composites: antibacterial, flame retardant, radar absorbing and self-healing,” Journal of Composite Materials, Vol. 49, 20, pp. 1–14, 2015. [2] Z. Huan, H. K. Chu, J. Yang, and D. Sun, “3D cell manipulation with honeycomb-patterned scaffold for regeneration of bone-like tissues,” Conference: IEEE International Conference on Information and Automation Lijiang, China, pp. 1680-1686, 2015. [3] N. Kartikasari, A. Yuliati, I. Listiana, D. Setijanto, K. Suardita, M. D. Ariani, and A. Sosiawan, “Characteristic of bovine hydroxyapatite/ gelatin / chitosan scaffolds as biomaterial candidate for bone tissue engineering,” Conference: IEEE EMBS Conference on Biomedical Engineering and Sciences (IECBES), Kuala Lumpur, pp. 623-626, 2016. [4] F. D. Ivan, V. Balan, M. Butnaru, I. M. Popa, and L. Verestiuc, “Bio-inspired calcium phosphates-biopolymer scaffolds with inclusions of SPIONs for bone tissue regeneration,” Conference: The 5th IEEE International Conference on E-Health and Bioengineering – EHB, Florina Cojocaru , 2015 [5] A. N. Hadi and J. K. Oleiwi, “Improving tensile strength of polymer blends as prosthetic foot material reinforcement by carbon fiber,” J. Material Sci. Eng., Vol. 4, 2, pp. 2169-0022, 2015. [6] B. Par , E. Lih, K. S. Par , Y. K. Joung, and D. K. Han, “Biopolymer based functional composites for medical applications,” Progress in Polymer Science, Elsevier Publisher, Vol. 68, pp. 77-105, 2017. [7] X. Han, H. Lin, X. Chen, X. Li, G. Guo, F. and Qu, “One step method for the preparation of poly methyl methacrylate modified titanium –bioactive glass three-dimensional scaffolds for bone tissue engineering,” IET Nanobiotechnology Journals, The Institutions of Engineering and Technology, Vol. 10, 2, pp. 45-53, 2016. [8] J. Henkel, M. A. Woodruf, D. R. Epari, R. Steck, V. Glatt, I. C. Dickinson, F. M. Choong, M. A. Schuetz, and D. W. Hutmacher, “Bone regeneration based on tissue engineering conceptions- A 21 St century perspective: review,” Journal of Biomaterials Science : Bone Research, Vol. 3, pp. 216-248, 2013. [9] B. Cimatti, E. E. Engel, M. H. N. Barbosa, P. D. Frighetto and J. B. Volpon, "Physical and mechanical characterization of a porous cement for metaphyseal bone repair,” Acta Ortop Bras., Vol. 23, 4, pp. 197-201, 2015. [01] V. Karageorgion, and D. Kaplan, "Porosity of 3D biomaterial scaffolds and osteogenesis,” Biomaterials, Vol. 26, pp. 5474-5491, 2005. [00] S. I. Salih, B. W. Salih, and O. S. Abdulghani, "Preparation and characterization some of the mechanical properties of polymer nano composite material used in structural applications,” Eng. & Tech. Journal, Vol. 34A, pp. 536-545, 2016. [12] M. M. Gad, R. Abualsaud, A. Rahoma, A. M. Al-Thobity, K. S. Al-Abidi, and S. Akhtar, "Effect of zirconium oxide nanoparticles addition on the optical and tensile properties of poly methyl methacrylate denture base material,” International Journal of Nano Medicine, Vol. 13, pp. 283-292, 2018. [13] P. J. Larkin, "Infrared and raman spectroscopy: principles and spectral interpretation,” 2nd Edition USA, Elsevier Publisher, 2011. [14] A. O. Alhareb, H. M. A il, and Z. A. Ahmad, “Impact strength, fracture toughness and hardness improvement of PMMA denture base through addition of nitrile rubber/ceramic fillers,” Saudi J. Dent. Res., Vol. 8, pp. 26–34, 2017. [05] M. R. Gharkan, B. I. Khalil, Ali A. H., S. A. Kadhum, and A. H. Aliwi, “Study of some properties for cold curing acrylic resin reinforced with nano yttrium oxide,” The Iraqi Journal for Medical And Materials Engineering, Vol. 18(1), pp. 136-145, 2018 . [06] N. Singh, and P. K. Khanna, "In situ synthesis of silver nano-particles in poly methyl methacrylate,” Materials Chemistry and Physics, Vol. 104, 2, pp. 367-372, 2007. [07] N. D. Singho, N. A. C. Lah, M. R. Johan, and R. Ahmad, “FTIR studies on silver-poly (methyl methacrylate) nanocomposites via in-situ polymerization technique,” Int. J. Electro-chem. Sci., Vol. 7, pp. 5596 – 5603, 2012. [08] D. E. Baciu, J. Simitzis, and D. G. Opowlos, “Synthesis and characterization of acrylic bone cement reinforced with zirconia–bioceramic,” Digest Journal of Nanomaterials and Biostructures, Vol. 7, 40, pp. 1779–1786, 2012. [09] P. Tamilselvi, A. Yelilarasi, M. Hema, and R. Anbarasan, “Synthesis of hierarchical structured MgO by sol-gel method,” NANO BULLETIN: Global Scientific Publishers, Vol. 2, pp. 1-5, 2013 . [01] M. M. Gad, R. Abualsaud, A. Rahoma, A. M. Al-Thobity, K. S. Al-Abidi, and S. A htar, “Effect of zirconium oxide nanoparticles addition on the optical and tensile properties of poly methyl methacrylate denture base material,” International Journal of Nano Medicine, Vol. 13, pp. 283-292, 2018 . [00] A. A. Fadhil, “Investigation of mechanical properties for hybrid polymer composite materials,” M.Sc. Thesis, Department of Mechanical Engineering, University of Al-Nahrain, Iraq, 2018. [00] D. S. A. Alhavaz, “Effect of untreated zirconium oxide nano filler on the flexural strength,” J Esthet Restor Dent., Vol. 29, 4, pp. 264-269, 2017. [23] S. I. Salih , J. K. Oleiwi, and S. Abd Al hidhir, “Comparative study of some mechanical properties of hybrid polymeric composites prepared by using friction stir processing,” Jour of Adv Research in Dynamical & Control Systems, Vol. 10, pp. 1316- 1326, 2018.
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