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Salivary and plasma analysis of oxidative stress biomarkers in end stage renal failure patients | ||
| Journal of baghdad college of dentistry | ||
| Article 1, Volume 23, Issue 2, 2011, Pages 46-50 | ||
| Authors | ||
| Raja H. Al-jubouri; Bahaa A. A. Al- Rahman Hadi | ||
| Abstract | ||
| ABSTRACTBackground: End Stage renal disease represents a clinical state or condition in which there has been an irreversibleloss of endogenous renal function. To evaluate role of oxidative stress & anti oxidant in chronic renal failure patientsby measuring malondialdehyde & uric acid in their plasma and saliva in comparison with apparently healthy controlgroup.Materials &methods: The study was conducted on 60 Chronic renal failure patients at Al-Hussein teaching hospital,Karbala (Iraq) & 30 apparently healthy control group. Laboratory measurements of salivary &plasma levels ofoxidants ,antioxidants markers (MDA, uric acid) was done on hemodialysis patients compared to age & sex matchedapparently healthy control group.Results: Salivary & plasma (malondialdehyde , uric acid ) showed highly significant differences between chronicrenal failure patients & apparently healthy control groups. This study was the first study that measure salivary MDA inend stage renal failure patients.Conclusion: Higher salivary, plasma oxidants & antioxidants concentrations of end stage renal failure patients withincrease salivary components disturbances in comparison with apparently healthy control group.Key wards: Hemodialysis, Malondialdehyde, Uric acid. (J Bagh Coll Dentistry 2011;23(46-50). | ||
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