Al-Khafaji, A., Hilal, A. (2020). Intrathecal Baclofen Therapy Effectiveness and Side Effects: A Retrospective Study. , 20(3), 227-232. doi: 10.52573/ipmj.2020.169711
Abd Al-Ameer Jasim Al-Khafaji; Aws Saad Hilal. "Intrathecal Baclofen Therapy Effectiveness and Side Effects: A Retrospective Study". , 20, 3, 2020, 227-232. doi: 10.52573/ipmj.2020.169711
Al-Khafaji, A., Hilal, A. (2020). 'Intrathecal Baclofen Therapy Effectiveness and Side Effects: A Retrospective Study', , 20(3), pp. 227-232. doi: 10.52573/ipmj.2020.169711
Al-Khafaji, A., Hilal, A. Intrathecal Baclofen Therapy Effectiveness and Side Effects: A Retrospective Study. , 2020; 20(3): 227-232. doi: 10.52573/ipmj.2020.169711

Intrathecal Baclofen Therapy Effectiveness and Side Effects: A Retrospective Study

Iraqi Postgraduate Medical Journal
Article 4, Volume 20, Issue 3, 2021, Pages 227-232    PDF (220.18 K)
Document Type: Research Paper
DOI: 10.52573/ipmj.2020.169711
Authors
Abd Al-Ameer Jasim Al-Khafaji1; Aws Saad Hilal2
1Iraqi Board for Medical Specializations, Baghdad, Iraq.
2Neurosurgical Hospital Baghdad, Iraq
Abstract
BACKGROUND:
Spasticity is a motor disorder characterized by a velocity-dependent increase in muscle tone with exaggerated tendon jerks, resulting from hyperexcitability of the stretch reflex, as a component of the upper motor neuron syndrome.
OBJECTIVE:
To evaluate the effect of intrathecal baclofen therapy after one to five years of treatment.
PATIENTS AND METHODS:
Aretrospective questionnaire-based study was done including 20 patients operated for intrathecal baclofen pump insertion at neurosciences hospital from 1/1/2013 to 1/1/2018,
RESULTS:
According to GMFCS in C.P, only those who were grade 4 or 3 had benefit, while grade 5 patients only improved easier diapering and transfer. From 8 spinal cord injury cases, 7 had improvement, while both M.S. cases were improved, but one of them started to have tolerance four years after implantation.  Eighteen out of 20 patients were satisfied from ITB therapy
One patient suffered from side effects (nausea, drowsiness) only after the test dose, and no side effects were mentioned during continuous therapy.
Two patients had drug tolerance were required to increase the dose.
CONCLUSION:
Intrathecal baclofen is a good treatment for spasticity, it can be considered safe as it caused no serious side effects, intrathecal baclofen is safer than oral baclofen because is uses a smaller dose, and it regarding tolerance, it occurs but not in every patient.
 
Keywords
Baclofen; Infusion pump; Intrathecal baclofen; Spasticity
References
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