Triglyceride and High density lipoprotein Cholesterol ratio in Patients with Acute Coronary Syndrome

Jawameer, Sherzad Saber; Saeed, Basil Najeeb

doi:10.32894/kjms.2021.170174

	Triglyceride and High density lipoprotein Cholesterol ratio in Patients with Acute Coronary Syndrome
Kirkuk Journal of Medical Sciences
Article 7, Volume 9, Issue 1, 2021, Pages 158-203 PDF (895.66 K)
Document Type: Original research
DOI: 10.32894/kjms.2021.170174
Authors
Sherzad Saber Jawameer^* ¹; Basil Najeeb Saeed²
¹MBChB, FIBMS, Internal Medicine Specialist, Azadi Teaching Hospital, Kirkuk, Iraq.
²FRCP ,MRCP ,MD ,DCC, Professor in internal medicine / cardiology, Department of Internal Medicine/Baghdad Teaching Hospital, College of Medicine, Baghdad University, Baghdad, Iraq
Abstract
*Background: Ischemic heart disease is the leading cause of death worldwide. This study assessed the prevalence of elevated triglyceride-to-HDL cholesterol ratio among acute coronary syndrome patients versus a control group, highlighting its role in atherogenesis. Methods:* A case-control study included 100 ACS inpatients and 100 non-ACS outpatients at Baghdad Teaching Hospital from July to November 2013. Demographic and clinical data were collected, and lipid profiles analyzed. *Result:* The TG/HDL-C ratio (≥5) was higher in 58% of ACS patients versus 10% of controls. ACS patients had significantly lower HDL-C and higher TG levels. Triglycerides varied by ACS type, being lowest in unstable angina and highest in STEMI and NSTEMI (P=0.031). *Conclusions:* High TG, low HDL-C, and elevated TG/HDL-C ratio are strongly associated with ACS, indicating their value as risk markers for early detection and prevention.
Keywords
Acute coronary syndrome; Hypertriglyceridemia; Atherosclerosis

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