Comparison of the Effect of Combined Infusion of Ephdrine and Phenylephrine, Ephdrine, or Phenylephrine in Prevention of Post Spinal Hypotension in Cesarean Section

Al-maʼini, Ali Hadi Muslih; Jamaʼan, Bushra Noori

doi:10.52573/ipmj.1970.174077

	Comparison of the Effect of Combined Infusion of Ephdrine and Phenylephrine, Ephdrine, or Phenylephrine in Prevention of Post Spinal Hypotension in Cesarean Section
Iraqi Postgraduate Medical Journal
Article 14, Volume 21, Issue 1, 2022, Pages 96-101 PDF (188.88 K)
Document Type: Research Paper
DOI: 10.52573/ipmj.1970.174077
Authors
Ali Hadi Muslih Al-maʼini¹; Bushra Noori Jamaʼan²
¹Al-Fallujah Teaching Hospital for Pediatrics and Maternity, Anbar, Iraq
²College of Medicine/ Al-Mustansyria University, Baghdad, Iraq
Abstract
BACKGROUND: Hypotension is the most common complication after spinal anesthesia for patients undergoing cesarean section. Prevention and treatment of post-spinal hypotension has been frequently investigated. AIM OF STUDY: Our study aimed to compare the effect of prophylactic infusion of combined ephedrine and phenylephrine, ephedrine, or phenylephrine alone in prevention of maternal hypotension after cesarean section. PATIENTS AND METHODS: 90 pregnant women that underwent elective cesarean delivery under spinal anesthesia were included and divided into: group A received an infusion of combined ephedrine and phenylephrine; group B received ephedrine infusion, and group C received phenylephrine infusion. Maternal parameters were recorded. RESULTS: There was an insignificant difference in demographic data among the groups. The maternal MAP shows no statistically significant difference, but the combined group shows less hypotensive episodes and less maternal side effects. CONCLUSION: Prophylactic infusion of ephedrine and phenylephrine combination can effectively decrease spinal anaesthesia related hypotension without any significant side effect.
Keywords
spinal anaesthesia; cesarean section; hypotension; ephedrine; Phenylephrine

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