SCIATIC NERVE REGENERATION USING AUTOTRANSPLANTATION OF TENDON WITH BONE MARROW IN DOGS

AlJobory, Ahmed Kh.

doi:10.23975/bjvetr.2022.174110

	SCIATIC NERVE REGENERATION USING AUTOTRANSPLANTATION OF TENDON WITH BONE MARROW IN DOGS
Basrah Journal of Veterinary Research
Article 29, Volume 12, Issue 1, 2013, Pages 309-322 PDF (2.2 M)
Document Type: Research Paper
DOI: 10.23975/bjvetr.2022.174110
Author
Ahmed Kh. AlJobory
Abstract
The aim of this study was to evaluate the regenerative activity of autotransplantation of superficial flexor digital tendon and bone marrow on the repair of sciatic nerve in dogs. Eight adult dogs from both sexes were used. The age ranges from 1-2 years and weight from 10-15 kgs. The animals were divided into two groups control and treatment group each group consists of four animals. Each animal in the first group was anesthetized with mixture of xylazine and ketamine at a dose of 5 mg/kg and 10 mg/kg of body weight I.M, respectively. The skin of the lateral surface of the thigh region was incised, fascia and muscle group were separated using blunt dissection, the left sciatic nerve was harvested and a 10 mm piece was transected. A segment longer than 10 mm of superficial flexor digital tendon was harvested and autografted using 5/0 nylon. In the second group animals underwent the same manner of first group as well as bone marrow applied at operative site. 60 days post operatively results exhibited improvement in activity of affected limb in treated animals with graft and bone marrow. Histologically there was an improvement at site of graft represented by formation of granulation tissue in both groups. In conclusion the local application of bone marrow on the site of tendon graft led to enhance the regeneration of sciatic nerve resulting in functional improvement of the affected limb
Keywords
Bone marrow; Sciatic; Tendon

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