The Effect of Sweet-tasting Foods Addiction on Appetite-related Hormones among Obese Adolescents

Rezaieg, Nour Shakir

doi:10.33091/amj.2021.174525

	The Effect of Sweet-tasting Foods Addiction on Appetite-related Hormones among Obese Adolescents
Al- Anbar Medical Journal
Article 4, Volume 18, Issue 1, 2022, Pages 15-20 PDF (542.52 K)
Document Type: Original articles
DOI: 10.33091/amj.2021.174525
Author
Nour Shakir Rezaieg^*
General Directorate of Education in Anbar, Gifted Guardianship Committee, Ministry of Education in Iraq, Anbar, Iraq.
Abstract
Background: Food ingestion and energy spending are organized through a complicated neurological system that involves both hypothalamic centers and peripheral satiety regulation (gastrointestinal and pancreatic hormones). Objectives: To assess the effects of sugar addiction on appetite-related hormones and metabolic hormones. Material and Methods: The study was done in two main hospitals in Anbar governorate, Iraq from April 2020 to November 2020. Concentration of fasting blood glucose (FBG), insulin, hormone insulin resistance (HOMA-IR), leptin, ghrelin, lipid profile, TSH, T3, and T4 were measured in the 54 obese adolescents and were compared with 54 normal-weight adolescents. Results: There was a significant increase in the concentrations of FBG, insulin, HOMA-IR, leptin, total cholesterol (TC), triacylglycerol (TAG), low-density lipoprotein cholesterol (LDL-C), and TSH in obese adolescents as compared to normal-weight adolescents (P-value < 0.05). While there was a significant (P < 0.05) decreased in the concentrations of ghrelin, high-density lipoprotein cholesterol (HDL-C), T3, and T4 in obese adolescents compared with normal-weight adolescents. The results also showed that there is a significant positive correlation between the concentration of leptin and each of BMI, FBG, insulin, and HOMA-IR, while there was a significant negative association between leptin level with HDL-C and ghrelin. Conclusion: Sweet-tasting meals are a major source of stimulation, which leads to overeating and thus leads to obesity.
Keywords
Leptin; Ghrelin; Sugar; Obesity; Adolescents; Insulin resistant

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