BACKGROUND:
Nasal polyps are considered to be the end results of a chronic inflammatory process in the sinonasal mucosa which are commonly seen in our routine ENT practice. Allergic fungal rhinosinusitis may be present with unilateral or bilateral polyps, it is important to be aware of the prevalence of allergic fungal rhinosinusitis in patients with nasal polyps.
OBJECTIVE:
To determine the frequency of allergic fungal rhinosinusitis among patients having nasal polyposis.
METHODS:
This is a descriptive cross-sectional study carried out in Department of Otolaryngology, Head and Neck Surgery, Ghazi Al-Hariri Hospital for surgical sub-specialties, during October 2018 to October 2019. A total of 55 patients (31 male, 24 female) with nasal polyposis for at least 3 months were enrolled. All patients were assessed by detailed history, examination, investigation including total Ig E titer, and Computed tomography of the nose and paranasal sinuses. These patients underwent endoscopic sinus surgery and the specimens were sent for histopathology for identification of fungus.
RESULTS:
The mean age was (32.9±12.4) years. Nasal obstruction (100%) was recorded, smell disturbance (86%) and nasal discharge (84%) were the commonest clinical presentation. Out of 55 patients, fungal elements were detected by histopathological study in 20(36%) of patients.
CONCLUSION:
Allergic fungal rhinosinusitis is significantly associated in patients with nasal polyposis.
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- Giles Warner, Andrea S. Burgess, Suresh Patel, Pablo Martinez-Devesa, Rogan Corbridge. OXFORD SPECIALIST HANDBOOKS Otolaryngology and Head and Neck Surgery. 2009; 21: 580-81.
- Melia L. Nasal Polyposis. In: Watkinson JC, Clarke RW. Scoot- Brown's otorhinolaryngology Head and Neck Surgery. 8th ed. London: Taylor and Frances Group: 2018:1038-43.
- Ryan MW. Chronic Rhinosinusitis with Nasal Polyposis. In: Johnson JT, Rosen CA. Bailey's Head and Neck Surgery Otolaryngology. 5th ed. Philadelphia: Wolters Kluwer. 2014: 525-32.
- Hedman J, Kaprio J, PoussaT, Nieminen MM. Prevalence of asthma,aspirin intolerance, nasal polyposis andchronic obstructive pulmonary disease ina population-based study. Int J Epidemio. 1999;28:717–22.
- Gan EC, Javer AR. Fungal Rhinosiusitis. In: Watkinson JC, Clarke RW. Scoot- Brown's otorhinolaryngology Head and Neck Surgery. 8th ed. London: Taylor and Frances Group: 2018:96:1047-57.
- Ni Mhurchu E, Ospina J, Janjua AS, Shewchuk JR, Vertinsky AT. Fungal Rhinosinusitis: A Radiological Review with Intraoperative Correlation. Can Assoc Radiol J. 2017;68:178-86.
- Adelson RT, Marple BF, Ryan MW, Aynehchi BB, Har-El G. Fungal Rhinosinusitis. Bailey's Head and Neck Surgery Otolaryngology. 5th ed. Philadelphia: Wolters Kluwer. 2014:37:557-71.
- Marple BF. Allergic Fungal Rhinosinusitis : Current Theories and Management Strategies. Laryngoscope. 2001;111:1006-19.
- Marple BF. Allergic fungal rhinosinusitis: a review of clinical manifestation and current treatment strategies. Med Mycol. 2006; 44:S277–84.
- 10. Gupta RP, Bahadur S, Thakar A, Handa KK, Sarkaar C. Management protocols of Allergic Fungal Sinusitis. Indian J Otolaryngol Head Neck Surg. 2007; 59:35-40.
- 11. Irshad-ul-Haq M, Farooq M, Qadri SH. Prevalence of allergic fungal sinusitis among patients with nasal polyps. JSZMC 2014:5:690-92.
- 12. Baloch ZA, Ahmad AN, Mahmood Z, et al. Frequency of allergic fungal sinusitis in patients with nasal polyps and its causative species. Pakistan Journal of Otolaryngology 2010;26:76-77.
- 13. Mian MY, Kamal SA, Senthikumaran G, Abdullah A, Pirani M . allergic fungal Rhinosinusitis :current status Pak J Otolaryngol 2002;18:36-4.
- 14. Zakirullah, Nawaz Ghareeb and Sattar Syed Fazle . Presentation and diagnosis of allergic fungal sinusitis. J Ayub Med Coll Abbottabad 2010; 22:53-57.
- 15. Bent JP 3rd, Kuhn FA. Diagnosis of allergic fungal sinusitis. Otolaryngol Head Neck Surg. 1994; 111:580-88.
- 16. Marple BF, Mabry RL. Allergic fungal sinusitis: Learning from our failures.Am J Rhinol 2000; 14:223–226.
- 17. Schubert MS. Allergic fungal sinusitis. Otolaryngol Clin North Am 2004; 37:301-26.
- 18. Gupta RP, Bahadur S, Thakar A, Handa KK, Sarkaar C. Management protocols of Allergic Fungal Sinusitis. Indian J Otolaryngol Head Neck Surg. 2007; 59:35-40
- 19. Laila M. Telmesani. Prevalence of allergic fungal sinusitis among patients with nasal polyps. Ann Saudi Med. 2009;29:212-14.
- 20. Kim JE, Kountakis SE. The prevalence of Samter's triad in patients undergoing functional endoscopic sinus surgery. Ear Nose Throat J .2007; 86:396-99.
- 21. Ferguson BJ. Eosinophilic mucin rhinosinusitis :a distinctive clinicopathological entity. Laryngoscope. 2000;799-813.
- 22. Bhardwaj BB, Gill JS, Singh T. The role of CT scan and histopathology in diagnosis of allergic fungal sinusitis .Clinic Rhinology :international journal ,2014;7:117-20.
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