A Short Review: Chemistry of Curcumin and Its Metal Complex Derivatives

Al-Noor, Taghreed; Ali, Ali; Al-Sarray, Ali; Al-Obaidi, Omar; Obeidat, Abeer; Habash, Reem

doi:10.37652/juaps.2022.174832

	A Short Review: Chemistry of Curcumin and Its Metal Complex Derivatives
Journal of University of Anbar for Pure Science
Article 4, Volume 16, Issue 1, 2022, Pages 20-26 PDF (617.62 K)
Document Type: Review Paper
DOI: 10.37652/juaps.2022.174832
Authors
Taghreed Al-Noor^* ¹; Ali Ali¹; Ali Al-Sarray²; Omar Al-Obaidi³; Abeer Obeidat⁴; Reem Habash⁴
¹Department of Chemistry. Ibn-Al-Haithem College of Education for pure science. University of Baghdad, Iraq
²Department of Chemistry, College of Science, University of Baghdad, Iraq.
³Chemistry Department, College of Science, University of Anbar, Iraq
⁴Department of Chemistry, Faculty of Science, Al-Balqa Applied University, Jordan
Abstract
This review covers recent progress in the synthesis of curcumin and the bioactivity of semisynthetic and synthetic analogs of curcumin. The review also shows how curcumin is a useful intermediate for the synthesis of more complex organic molecules; historical perspective; the process of preparing the metal complexes and characterization the produced complexes using various spectral and other techniques; shows the importance of curcumin and its derivatives for their potential applications in medical devices and broad-spectrum of medical application such as antibiotic ointment, alternative therapeutics, antifungal, and antibacterial activities.
Keywords
Curcumin; antibacterial activity.antibiotic resistance.alternative therapeutics.metalcomplexes.Anticancercompounds. Prodrugs.Bioinorganic chemistry

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