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Effect of paracetamol in chromosomal aberration and sperm abnormalities of germinal cells in white mice | ||
| iraq journal of market research and consumer protection | ||
| Article 1, Volume 1, Issue 1, 2009, Pages 1-13 | ||
| Authors | ||
| A. R. Al-Amery; S. M. Nada | ||
| Abstract | ||
| Paracetamol is a widely used as analgesic and antipyretic. It is a viable at all pharmacies and you can get it without special medical prescript over dosage of paracetamol can cause a serious damages like liver necrosis or muscle atrophy on acute condition it also cause damages for kidneys and pancreases functions. The aim of study to detect the cytogenetic effects of paracetamol drug through using cytogenetic analysis on the germ cells and sperms abnormalitics in white mice. The result showed that two concentration of paracetamol (50 and 100) mg/kg caused a reduction in the mitotic index, increasing in the chromosomal aberrations, abnormalities in the sperms shape, reduction in the percent of the viable normal sperm and reduction sperm motility. | ||
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