Synthesis and Study Biological Activities of Sulfur - Containing Drugs

Saeed, Zainab F.; Saleh, Mohanad Yakdhan; Sadeek, Ghufran Th.

doi:10.33899/rjs.2023.178632

	Synthesis and Study Biological Activities of Sulfur - Containing Drugs
Rafidain Journal of Science
Volume 32, Issue 2, June 2023, Pages 81-97 PDF (1.26 M)
Document Type: Review Paper
DOI: 10.33899/rjs.2023.178632
Authors
Zainab F. Saeed¹; Mohanad Yakdhan Saleh^* ²; Ghufran Th. Sadeek^* ³
¹Department of Physiology, Biochemistry, and Pharmacology/ College of Veterinary Medicine/ University of Mosul
²Dept. of Chem., College of Education for pure Scienceو Mosul University, Mosul,IRAQ
³Department of Chemistry/ College of Education for Pure Science/ University of Mosul
Abstract
The importance of developing sulfur therapy is crucial to achieving the progress of pharmaceutical works - functional groups produced from sulfur can be found in a wide range of medicines due to the components of various biological and pharmaceutical effects. Sulfur compounds are an important class of chemical molecules. It can be used in various areas of chemistry. As a result of the widespread of pharmaceutical compounds containing sulfur, it gave great importance, as there are many drugs that have been developed, such as mafenide, sulfacetamide, Sulfadiazine, sulfamethazine, Sulfasalazine, sulfisoxazole. The study dealt with collecting the most important methods of preparing organic sulfur compounds. The focus was on thiols, thiones and sulfones, and a comparison was made between the pharmaceutical compounds that are included in their compositions in terms of synthesis and medical uses as antibacterial, antifungal and anticancer cells.
Keywords
sulfonamide; sulfone; pharmaceutical; drugs sulfur

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