Mohammed, N., Ahmed, H., Jarad, N., Al-Shabbani, A. (2020). Haemonchus contortus: Review of recent molecular advances in anthelmintic resistance and vaccination. , 19(2), 15-26. doi: 10.29079/qjvms.2020.179345
Nuha Qasim Mohammed; Hiba Shehab Ahmed; Noor Idan Jarad; Amal Hassan Al-Shabbani. "Haemonchus contortus: Review of recent molecular advances in anthelmintic resistance and vaccination". , 19, 2, 2020, 15-26. doi: 10.29079/qjvms.2020.179345
Mohammed, N., Ahmed, H., Jarad, N., Al-Shabbani, A. (2020). 'Haemonchus contortus: Review of recent molecular advances in anthelmintic resistance and vaccination', , 19(2), pp. 15-26. doi: 10.29079/qjvms.2020.179345
Mohammed, N., Ahmed, H., Jarad, N., Al-Shabbani, A. Haemonchus contortus: Review of recent molecular advances in anthelmintic resistance and vaccination. , 2020; 19(2): 15-26. doi: 10.29079/qjvms.2020.179345

Haemonchus contortus: Review of recent molecular advances in anthelmintic resistance and vaccination

Al-Qadisiyah Journal of Veterinary Medicine Sciences
Volume 19, Issue 2, June 2020, Pages 15-26    PDF (276.36 K)
Document Type: Review Paper
DOI: 10.29079/qjvms.2020.179345
Authors
Nuha Qasim Mohammed1; Hiba Shehab Ahmed2; Noor Idan Jarad1; Amal Hassan Al-Shabbani3
1College of Veterinary Medicine, University of AL-Qadisiyah, Iraq
2College of Biotechnology, University of AL-Qadisiyah, Iraq.
3College of Pharmacy, University of AL-Qadisiyah, Iraq
Abstract
Haemonchus contortus is one of the world's major financial worms that attack ruminants. It is a blood-sucking parasite founded in the abomasum, particularly in cattle, sheep, and goats. Nematode infections may cause anemia, weight loss, or even death in animals that are severely affected. Current management practices against H. contortus largely depend on regular anthelmintic therapies in all countries with varying incidence across various regions. H. contortus thus aims to form new action techniques in order to overcome resistance to anthelmintic agents. One option is a logical approach focused on a thorough knowledge of the molecular pathways in growth and reproduction cycles in the manufacture in modern anti-parasite drugs and vaccines. Key molecules may be defined as potential drug targets by a simple description of molecular, biochemical functions. Besides, it is immediately essential to formulate immunological control of farm animal nematode infections. Important prevention has been accomplished after vaccination with native protein extracts, which shows that vaccination is possible. This paper explores the success of H. contortus science in the world. Particular fields of concern include epidemiological research, genetic analysis, and anthelmintic resistance identification using traditional and molecular techniques; morphological and chemical research of crucial molecules in mechanism expansion, parasitic organism-host interaction, and vaccine research. In the suggested form of these opinions, areas for potential exploration and alternatives for new or revised prevention strategies are described.

 
Keywords
Control; Vaccination; genetic; Haemonchus contortus; Ruminant
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