Jabar, M., Alnakash, A., Al-Jubouri, S. (2023). The Anti-Mullerian Hormone Levels In Polycystic Ovary Syndrome And Its Relation To Body Mass Index. , 22(4), 473-480. doi: 10.52573/ipmj.2023.182305
Muna Sabah Jabar; Abdulrazak H. Alnakash; Saba Kamal Al-Jubouri. "The Anti-Mullerian Hormone Levels In Polycystic Ovary Syndrome And Its Relation To Body Mass Index". , 22, 4, 2023, 473-480. doi: 10.52573/ipmj.2023.182305
Jabar, M., Alnakash, A., Al-Jubouri, S. (2023). 'The Anti-Mullerian Hormone Levels In Polycystic Ovary Syndrome And Its Relation To Body Mass Index', , 22(4), pp. 473-480. doi: 10.52573/ipmj.2023.182305
Jabar, M., Alnakash, A., Al-Jubouri, S. The Anti-Mullerian Hormone Levels In Polycystic Ovary Syndrome And Its Relation To Body Mass Index. , 2023; 22(4): 473-480. doi: 10.52573/ipmj.2023.182305

The Anti-Mullerian Hormone Levels In Polycystic Ovary Syndrome And Its Relation To Body Mass Index

Iraqi Postgraduate Medical Journal
Volume 22, Issue 4, October 2023, Pages 473-480    PDF (250.2 K)
Document Type: Review Article
DOI: 10.52573/ipmj.2023.182305
Authors
Muna Sabah Jabar1; Abdulrazak H. Alnakash* 2; Saba Kamal Al-Jubouri3
1Obstetrics and Gynecology dept., Al-Elwiya Maternity Teaching Hospital, Baghdad, Iraq
2Alkindy College of Medicine, University of Baghdad, Al-Elwiya Maternity Teaching Hospital, Baghdad, Iraq
3Family Medicine, Nutrition Research Institute Public Health Directorate, Baghdad, Iraq
Abstract
BACKGROUND:
Anti-mullerian hormone level reflects the ovarian follicular reserve and considered as sensitive marker of ovarian aging. Although the ultimate pathogenesis of polycystic ovary syndrom remains obscure,             the distinictive feature is a failure of follicular maturation resulting in anovulation and accumulation of pre-antral and small antral follicles which contribute significantly to the production of anti-mullerian hormone.
OBJECTIVE:
To evaluate the anti-mullerian hormone levels in polycystic ovary syndrome women and to explore its relation with body mass index.
STUDY DESIGN:  
Cross section study.
Setting: Department of Gynecology and Obstetrics at Al-Elwiya Maternity Teaching Hospital.
MATERIALS AND METHODS: 
One hunderd women suffering from polycystic ovary syndrom  (18-37 years old) were included in                   the study and arranged in three groups according to their body mass index: first group, 30 of them, were having normal body weight (body mass index 18.5 to 24.9kg/m2) and second group, 59 participants with body mass index 25 to 29.9kg/m2 and third group, 11 women, their body mass index ≥ 30kg/m2.                  Blood sample was collected from them after taking a detailed history and assessment according to                the questioner form and the results were compared among the groups.
RESULTS:
Increase in body mass index is found to be accompanied with  decrease in anti-mullerian hormone levels (P <0.05), with mean anti-mullerian hormone level significantly decreases as body mass shifts up from normal to overweight to obesity (8.5, 6.4 & 4.4 ng/mL respectively) (P <0.05). Anti-mullerian hormone level did not significantly correlate with  age of those women (P >0.05).
CONCLUSION:
An inverse correlation had been found between anti-mullerian hormone levels and body mass index in women with polycystic ovary syndrome.
 
Keywords
Anti-mullerian hormone; Body mass index; polycystic ovary syndrome
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