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Seroppositivity of anti-rubella antibodies among premarriagegirls in Diyala province | ||
| Diyala Journal For Pure Science | ||
| Article 1, Volume 7, Issue 3, 2011, Pages 259-267 | ||
| Authors | ||
| Adnan A. Neima; Abbas A. Al-Duliami; Abdul-Razak SH. Hasan | ||
| Abstract | ||
| Rubella is the mildest of common viral exanthems. However, infection during earlypregnancy may result in serious abnormalities of the fetus including congenital malformationand mental retardation. The objectives of the present study are to determine the seropositivityrate of anti-rubella IgG and IgM antibodies among premarriage girls in Diyala province.A total of 358 subjects were included in the present study. The study was extendedfrom 7/April/2007 to 30/September/2008. 186 (51.9%) were females with mean age 16.7±2.1 years, and 172(48.1%) were males with mean age 24.5 ±5.5 years. Those subjects wererandomly selected from those attending the Public Health Laboratory in Baquba forpremarriage investigations. Further information regarding age, residence, educational levelswas taken by personal interview. Detection of anti-rubella antibodies was done by enzymelinkedimmunosorbant assays (ELISA) using (Biokit, Spain).Data were statistically analyzedusing SPSS version 13 computer assisted processing. P value <0.05 was consideredsignificant.The results showed that all males and females were negative for anti-rubella IgMantibody. However, 168 (97.7%) of males and 170(91.4%) of females were positive for antirubellaIgG antibody. Therefore, the rate of non-immune females was higher than that ofmales (8.6% vs 2.3%). In conclusion premarital screening for anti-rubella IgG and vaccinationof non-immune girls could minimize the risk of rubella infection during pregnancy and childbearingperiod.Key words: Rubella, Congenital rubella syndrome, premarriage girls | ||
| Keywords | ||
| Seroppositivity; nti; rubella antibodies among premarriagegirls | ||
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